Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2018 | Month : June | Volume : 12 | Issue : 6 | Page : CC11 - CC13

Auditory and Visual Reaction Time in Polycystic Ovarian Syndrome

Rupali Mehta, Manjinder Kaur, Pooja Gandhi, Priyanka Parihar

1. Student, Department of Physiology, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India. 2. Professor and Head, Department of Physiology, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India. 3. Consultant, Department of Geetanjali Fertility Centre, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India. 4. Student, Department of Physiology, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India.

Correspondence Address :
Dr. Manjinder Kaur,
Professor and Head, Department of Physiology, Geetanjali Medical College and Hospital, Udaipur-313002, Rajasthan, India.
E-mail: drmanjinder@yahoo.com

Abstract

Introduction: Polycystic Ovarian Syndrome (PCOS) is a hormonal disorder of female reproductive system causing infertility, irregular menstrual cycle and hormonal imbalance characterised by hyperestrogenemia, hyperprolactinemia, increased Anti Mullerian Hormone (AMH) and Thyroid Stimulating Hormone (TSH). Apart from the role in female reproductive system, these hormones are shown to have neuromodulatory role, affecting the neuronal activity. Thus, the auditory and visual reaction time may be affected in the women with polycystic ovaries.

Aim: To evaluate the auditory and visual reaction time, in patients with polycystic ovarian syndrome.

Materials and Methods: The study was designed as a case-control study where the 80 otherwise healthy women, attending infertility OPD, were recruited for the study and divided into groups viz., PCOS (n=40) and NPCOS (n=40). The subjects from both the groups were evaluated for their anthropometric data, hormone levels {Serum estrogen, Serum prolactin, Serum TSH, Serum AMH} using COBAS-6000 analyser along with the auditory and visual reaction time using RTM-608 (Medicaid). The observations were recorded and analysed using paired t-test.

Results: Auditory reaction time had significantly decreased (p=0.012) while visual reaction time was non-significantly reduced in Group PCOS as compared to Group NPCOS.

Conclusion: The altered hormonal profile in PCOS i.e., hyperestrogenemia and hyperprolactinemia exerts enhanced neuromodulatory action through neural ERa receptors and tuberoinfundibular dopaminergic neurons in hypothalamus, thus resulting in increased neuronal excitability and decreased reaction time in patients with PCOS.

Keywords

Anti mullerian hormone, Prolactin, Reaction time

How to cite this article :

Rupali Mehta, Manjinder Kaur, Pooja Gandhi, Priyanka Parihar. AUDITORY AND VISUAL REACTION TIME IN POLYCYSTIC OVARIAN SYNDROME. Journal of Clinical and Diagnostic Research [serial online] 2018 June [cited: 2018 Aug 16 ]; 12:CC11-CC13. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=June&volume=12&issue=6&page=CC11-CC13&id=11646

DOI and Others

DOI: 10.7860/JCDR/2018/31863.11646

Date of Submission: Jul 24, 2017
Date of Peer Review: Oct 06, 2017
Date of Acceptance: Mar 30, 2018
Date of Publishing: Jun 01, 2018

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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