Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2017 | Month : September | Volume : 11 | Issue : 9 | Page : TC06 - TC09

Radiological Manifestations of Pulmonary Tuberculosis - A Comparative Study between Immunocompromised and Immunocompetent Patients

Manoj Mathur, Rajesh K Badhan, Sudesh Kumari, Navkiran Kaur, Saryu Gupta

1. Associate Professor, Department of Radiology, Government Medical College and Rajindra Hospital, Patiala, Punjab, India. 2. Senior Resident, Department of Radiology, Government Medical College and Rajindra Hospital, Patiala, Punjab, India. 3. Medical Officer, Department of Respiratory Diseases and Tuberculosis, Government Medical College and Rajindra Hospital, Patiala, Punjab, India. 4. Professor, Department of Radiology, Government Medical College and Rajindra Hospital, Patiala, Punjab, India. 5. Assistant Professor, Department of Radiology, Government Medical College and Rajindra Hospital, Patiala, Punjab, India.

Correspondence Address :
Dr. Rajesh K Badhan,
H. No.-47, SST Nagar, Patiala -147003, Punjab, India.
E-mail: rkbadhan@yahoo.co.in

Abstract

Introduction: Pulmonary tuberculosis has atypical radiological manifestations in patients with underlying immunocompromised disease like diabetes and human immunodeficient virus infection. Computed tomography has important role in such patients for early diagnosis of disease and management to minimize complication.

Aim: To evaluate and compare the computed tomography chest features of pulmonary tuberculosis in between immunocompromised patients and immunocompetent patients.

Materials and Methods: This cross-sectional study was conducted in the hospital on newly diagnosed 60 pulmonary tuberculosis patients of which 30 patients had no underlying disease (Immunocompetent Group) and 30 patients had diabetes mellitus or were human immunodeficiency virus seropositive (Immunocompromised Group). CT scan of chest were evaluated for each patient.

Results: In immunocompetent patients, 36.7% had radiologically atypical presentation,90% had nodular opacities, 73.3% had consolidation, 23.3% had lymphadenopathy, 60% had cavitation and cavitatory lesion were single in 94.4% patients. Isolated upper lung field were involved in 60% patients. In immunocompromised patients 76.7% had radiologically atypical presentation, 66.7% had nodular opacities, 46.7% had consolidation, 63.3% had lymphadenopathy, 20% had cavitation and cavitatory lesions were multiple in 60% patients. Isolated lower lung field were involved in 23.3% patients.

Conclusion: We concluded that immunocompromised patients have more atypical involvement of lung fields, higher prevalence of lymphadenopathy as compared to immunocompetent patients. Diabetic patients have multiple cavitatory lesions as compared to non-diabetic patients. HIV seropositive patients have more prevalence of lymphadenopathy as compared to HIV seronegative patients.

Keywords

Computed tomography, Diabetes mellitus, Human immunodeficient virus

How to cite this article :

Manoj Mathur, Rajesh K Badhan, Sudesh Kumari, Navkiran Kaur, Saryu Gupta. RADIOLOGICAL MANIFESTATIONS OF PULMONARY TUBERCULOSIS - A COMPARATIVE STUDY BETWEEN IMMUNOCOMPROMISED AND IMMUNOCOMPETENT PATIENTS. Journal of Clinical and Diagnostic Research [serial online] 2017 September [cited: 2017 Nov 19 ]; 11:TC06-TC09. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=September&volume=11&issue=9&page=TC06-TC09&id=10535

DOI and Others

DOI: 10.7860/JCDR/2017/28183.10535

Date of Submission: Mar 08, 2017
Date of Peer Review: Mar 31, 2017
Date of Acceptance: Aug 16, 2017
Date of Publishing: Sep 01, 2017

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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