Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Year : 2017 | Month : September | Volume : 11 | Issue : 9 | Page : ED06 - ED08

Approach to a Pregnant Woman with Anti D + Anti C Reactivity Pattern: A Diagnostic Conundrum

Preeti Rai, Geetika Sharma, Deeksha Singh, Jyoti Garg

1. Associate Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India. 2. Assistant Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India. 3. Senior Resident, Department of Pathology, Lady Hardinge Medical College, New Delhi, India. 5. Senior Resident, Department of Pathology, Lady Hardinge Medical college, New Delhi, India.

Correspondence Address :
Dr. Deeksha Singh,
C1/04, Mangal Apartments, Vasundhara Enclave-110096, Delhi, India.
E-mail: deepshikha.singh293@gmail.com

Abstract

The Rhesus G antigen is present on all RBCs that are C+ and also on most D+ RBCs. Due to this co-distribution of G with either C or D antigen, it mimics a reactivity pattern of anti C + anti D on Indirect Antiglobulin Test (IAT), though the role of Anti G in causing Hemolytic Disease of Newborn (HDN) is controversial. The differentiation of anti D, anti C, and anti G is essential particularly in pregnant females. We hereby report a rare case of anti G with anti D and anti C in a pregnant woman with emphasis on approach to identify anti D+C+G and its implications.

Keywords

Alloimmunisation, Anti D, Anti C, Anti G, Haemolytic, Irregular erythrocyte antibodies, Pregnancy

How to cite this article :

Preeti Rai, Geetika Sharma, Deeksha Singh, Jyoti Garg. APPROACH TO A PREGNANT WOMAN WITH ANTI D + ANTI C REACTIVITY PATTERN: A DIAGNOSTIC CONUNDRUM. Journal of Clinical and Diagnostic Research [serial online] 2017 September [cited: 2017 Nov 20 ]; 11:ED06-ED08. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=September&volume=11&issue=9&page=ED06-ED08&id=10550

DOI and Others

DOI: 10.7860/JCDR/2017/27902.10550

Date of Submission: Feb 28, 2017
Date of Peer Review: Apr 25, 2017
Date of Acceptance: May 08, 2017
Date of Publishing: Sep 01, 2017

FINANCIAl OR OTHER COMPETING INTERESTS: None.

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