Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Year : 2017 | Month : October | Volume : 11 | Issue : 10 | Page : ZE01 - ZE05

Gene Therapy Applications in Dentistry: A Review

Dinesh Francis Swamy, Sapna Sada Raut Dessai, Elaine Savia Barretto, Kathleen Manuela DSouza

1. Lecturer, Department of Paediatric Dentistry, Goa Dental College and Hospital, Panaji, Goa, India. 2. Lecturer, Department of Oral Medicine and Radiology, Goa Dental College and Hospital, Panaji, Goa, India. 3. Lecturer, Department of Paediatric Dentistry, Goa Dental College and Hospital, Panaji, Goa, India. 4. Lecturer, Department of Prosthodontics, Goa Dental College and Hospital, Panaji, Goa, India.

Correspondence Address :
Dr. Dinesh Francis Swamy,
Lecturer, Department of Paediatric Dentistry, Goa Dental College and Hospital, Panaji, Goa-403202, India.
E-mail: dfswamy@gmail.com

Abstract

Gene therapy involves transfer of new genetic material or manipulation of the existing material for the purpose of treating human disease. It involves transfer of genetic material – ex vivo and in vivo and may conceivably revolutionize clinical practice in the coming years. Although progress has chiefly been in the medical domain, research has moved to various dental conditions as well. This review is presented to highlight various applications of gene therapy in dentistry in the areas such as salivary gland disorders, chronic pain, DNA vaccines, bone repair, implantology, head and neck cancer, orthodontic therapy, periodontal repair and tooth regrowth.

Keywords

Bone Repair, Gene transfer techniques, Growth factor, Neoplasms

How to cite this article :

Dinesh Francis Swamy, Sapna Sada Raut Dessai, Elaine Savia Barretto, Kathleen Manuela DSouza. GENE THERAPY APPLICATIONS IN DENTISTRY: A REVIEW. Journal of Clinical and Diagnostic Research [serial online] 2017 October [cited: 2017 Oct 23 ]; 11:ZE01-ZE05. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2017&month=October&volume=11&issue=10&page=ZE01-ZE05&id=10703

DOI and Others

DOI: 10.7860/JCDR/2017/28150.10703

Date of Submission: Mar 06, 2017
Date of Peer Review: May 08, 2017
Date of Acceptance: Aug 23, 2017
Date of Publishing: Oct 01, 2017

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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