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With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
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On May 11,2011




Dr. Shankar P.R.

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On Jan 2020

Important Notice

Case report
Year : 2023 | Month : October | Volume : 17 | Issue : 10 | Page : KD01 - KD03 Full Version

Conservative Management of Osteoarthritis with Hypertension and Ischaemic Heart Disease through Ayurvedic Treatment: A Case Report


Published: October 1, 2023 | DOI: https://doi.org/10.7860/JCDR/2023/64381.18588
Satyajit Pandurang Kulkarni, Pallavi Satyajit Kulkarni

1. Professor, Department of Panchakarma, Manjushree Research Institute of Ayurvedic Science, Piplaj, Gujarat, India. 2. Associate Professor, Department of Agadtantra Avum Vidhivaidyak, Manjushree Research Institute of Ayurvedic Science, Piplaj, Gujarat, India.

Correspondence Address :
Satyajit Pandurang Kulkarni,
Flat No. D 303, Brij Orcidkh Road, Near Pramukh Plots, Vavol, Gandhinagar-382610, Gujarat, India.
E-mail: satyajitkulkarni2001@gmail.com

Abstract

The ayurvedic management of osteoarthritis is well known, but the management of arthritis with co-morbidities such as hypertension, ischaemic heart disease, obesity, and lumbar spondylosis through Ayurvedic treatment is yet to be discovered. In the present case, a 50-year-old female presented with complaints of mild to moderate pain in the lower back region, legs, knee joints, and swelling over both knees for five years. She also had a history of hypertension and IHD for 10 years and had been taking Non Steroidal Anti-inflammatory Drugs (NSAIDs) without any relief. Seeking Ayurvedic treatment, the patient discontinued NSAIDs and underwent Panchakarma for four weeks. The treatment resulted in significant pain relief, improved VAS score, and increased walking distance. The present case report provides a detailed ayurvedic treatment protocol for managing arthritis with co-morbidities such as hypertension, ischaemic heart disease, obesity, and lumbar spondylosis.

Keywords

Arthritis, Ayurvedic medicine, Co-morbidities, Panchakarma

Case Report

A 50-year-old female presented at Goenka Hospital in Gandhinagar, Gujarat, for Ayurvedic treatment of various complaints, including pain in the lower back region, legs, and knee joints, as well as swelling in both knees with restricted movements for the past five years. The pain was continuous, mild to moderate in nature, and usually aggravated by physical activities. The pain in her left leg was more intense than in her right leg. Additionally, the patient experienced worsened low back pain in the early morning.

The patient had a history of hypertension and IHD for 10 years and was receiving regular treatment. She began experiencing pain in her knees and lower back five years ago and had been taking NSAIDs, which did not provide any relief. As a result, she sought ayurvedic treatment refer to (Table/Fig 1).

During the examination, she was found to be obese, with a body weight of 74 kg and a height of 5 feet 2 inches (BMI 30). There was moderate fat accumulation in both the abdomen and hip joints. Slight swelling was observed in both knee joints, with the left knee being more affected than the right. Additionally, crepitus was detected in both knee joints. The patient was unable to walk more than 10 steps. However, her vital signs, including temperature, pulse rate, and blood pressure, were within normal ranges. The Visual Analogue Scale (VAS) score was 6/10 for the right leg, 7/10 for the left leg, and 6/10 for the low back.

She was diagnosed with Sthaulya and Aamvata according to Ayurvedic principles. She was placed on ayurvedic treatment for Four weeks avoiding the use of NSAIDs. However, modern medicines for HTN and IHD were continued.

During her four-week stay at the hospital, drugs were prescribed for Aama Dosha for the initial four days. Panchakarma called ‘Udvartana’ (heated 500 gm of Triphala powder and used as a massage aid) was administered once in the morning along with Trayodashang Guggul (250 mg twice a day), Medohara Vati (250 mg twice a day), Rasnadi Kashayam (10 mL twice a day), and Ajmodadi Churna (1 gm twice a day) orally with hot water. Additionally, Panchakarma treatments such as oil massage, sudation, Katibasti, and Janubasti were administered as required (Table/Fig 2),(Table/Fig 3).

Follow-up was done based on two assessment parameters:

1. The self-reported Visual Analogue Scale (VAS): A self-reported VAS scale was used to measure knee joint pain, leg pain, and low back pain. The scale ranged from 0 (indicating no pain) to 10 (indicating unbearable pain). Every day, during the morning round (10-10:30 AM). It can be observed that there was a progressive decrease in the self-reported VAS scale, except on 15th June 2022, when the patient experienced aggravated symptoms (Table/Fig 4). After being discharged, the patient reported decreased pain levels. The VAS score for the left leg decreased from 7/10 to 2/10, while the right leg decreased from 6/10 to 3/10. The low back pain also significantly reduced from 6/10 to 1/10.

2. Walking distance: The patient was asked to walk independently every morning until she could. The distance was measured daily, and the mean length was 19.27 metres (range: 7-50 metres). The walking distance gradually increased from 7 metres on the first day to 50 metres on the 28th day.

Discussion

Ayurvedic treatments involving dry powder massage, followed by massage with sesame oil, hot fomentation, Kati Basti, Janu Basti, and oral Ayurvedic drugs have significantly relieved pain, edema, and restricted movements in patients with osteoarthritis who also have a history of HTN, lumbar spondylosis, obesity, and IHD.

Ayurveda consultants widely treat arthritis with ayurvedic medicines and Panchakarma. However, when arthritis co-exists with HTN or IHD, they usually refer such cases to modern medical specialists. In this particular case. The ayurvedic treatment effectively provided relief for arthritis symptoms co-existing with HTN, IHD, obesity and lumbar spondylosis.

Research conducted by Grampurohit PL et al., focused on treating 25 cases of osteoarthritis with a Panchakarma method called Anuvasan Basti using Ksheerbala oil for 10 consecutive days, without any internal medication. A follow-up was conducted after 20 days to evaluate the results. The study observed a significant reduction in pain, swelling, tenderness, and crepitus without any radiological changes (1). However, the present study excluded osteoarthritis cases with hypertension or IHD.

In the present case study, personalised medication was utilised through various Panchakarma procedures such as Udvartana, massage, and hot fomentation to treat a patient with osteoarthritis, hypertension, and IHD. Ayurveda’s philosophy emphasises the importance of tailored treatments for each individual.

A case of Motor Neuron Disease (MND) was treated for almost a year using Panchakarma procedures such as Udvartana, Swedana, and oral Ayurvedic medication, as reported by Policepatil BV (2).

The study showed a significant increase in the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) from 29 before the treatment to 38 after the treatment, indicating positive improvement in speech, swallowing, food cutting, climbing, orthopnoea, and salivation. However, the patient in this case did not have a history of arthritis, hypertension, IHD, or lumbar spondylosis. The similarity between the present case and the current case is that both used Udavartana and Swedana for Panchakarma treatment, as both diseases are Vata dominant, according to Ayurveda.

In a study conducted by Rajoria K et al., limb girdle dystrophy was treated using different Panchakarma procedures (3). Similarly, Rohit S and Rahul M used Panchakarma procedures like Snehana (external oleation), Swedana (passive heat therapy), Hrudaydhara (concoction dripping treatment), and Basti (enema) twice a day for seven days, followed by Kadha ARJ et al., for the next 30 days in patients with Congestive Heart Failure (CHF) (4). The effect was assessed using Maximum Aerobic Capacity (MAC) uptake. A significant improvement was seen in MAC levels on the seventh day (7.11% p=0.029) compared to the baseline. This improvement remained stable during the two follow-ups on the 30th and 90th days. In the present case report, the patient had a history of IHD and hypertension with arthritis and lumbar spondylosis. Therefore, in the present case, Panchakarma procedures were used, but they were slightly modified based on the disease condition.

A clinical trial conducted by Sane R et al., demonstrated the effectiveness of heart failure reversal treatment as an additional therapy for patients with chronic heart failure (5). The trial involved 70 patients, with one group receiving Heart Failure Reversal Therapy (HFRT) in addition to the Standard CHF Treatment (SCT), while the other group only received SCT. The results showed that HFRT improved the functional capacity of CHF patients without any safety concerns. In the current case study, some of the Panchakarma procedures were administered similarly to the aforementioned trial.

Rastogi S and Chiappelli F found improvement in blood pressure and pulse rate in hypertensive patients who were given Sarvang Swedana (6). In the present case study, as the patient was a known hypertensive, the observational study by Rastogi S and Chiappelli F provided a basis for performing Panchakarma (Swedana) in the present case study (6). An in-vitro study revealed that Trayodashang Guggul had anti-inflammatory and antioxidant properties. It also inhibited membrane stabilising, protein denaturation inhibitory, antilipoxygenase, and antiproteinase activities (7). Trayodashang Guggul has been used in this case report as well. Similarly, Ajmodadi Churna was found to exhibit anti-inflammatory activity by mediating prostaglandins (8).

Both panchakarma and ayurvedic medicines have been effective in treating uncomplicated cases of arthritis. However, this particular case provided a detailed insight into the treatment protocol for arthritis accompanied by several other health conditions such as HTN, IHD, obesity, and lumbar spondylosis. Therefore, Ayurvedic treatment can also be considered as an alternative treatment modality when arthritis patients present with such co-morbidities.

Conclusion

Arthritis patients who also suffer from co-morbidities like HTN, IHD, obesity, and lumbar spondylosis are usually referred to modern medical specialists. However, the present case report shows that these patients can find relief through Ayurvedic treatments such as Panchakarma and Ayurvedic medicines. Ayurvedic consultants can now treat arthritis through Ayurvedic medicines and Panchakarma when arthritis co-exists with the above-mentioned conditions.

Acknowledgement

The authors acknowledge the hospital staff of Goenka Hospital and the Panchakarma staff for their service.

References

1.
Grampurohit PL, Rao N, Harti SS. Effect of anuvasana basti with ksheerabala taila in sandhigata vata (Osteoarthritis). Ayu. 2014;35(2):148. Available from: /pmc/articles/PMC4279320/. [crossref][PubMed]
2.
Policepatil BV. A case report: Ayurvedic intervention in motor neuron disease contemplating Kaphavrutavata. J Ayurveda Integr Med. 2022;13(2):100548. [crossref][PubMed]
3.
Rajoria K, Singh SK, Dadhich S. Ayurvedic management in limb girdle muscular dystrophy-A case report. J Ayurveda Integr Med [Internet]. 2022;13(1):100486. Available from: https://pubmed.ncbi.nlm.nih.gov/34961685/. [crossref][PubMed]
4.
Rohit S, Rahul M. Efficacy of heart failure reversal treatment in patients with low ejection fraction. J Ayurveda Integr Med [Internet]. 2018;9(4):285. Available from: /pmc/articles/PMC6314236/. [crossref][PubMed]
5.
Sane R, Aklujkar A, Patil A, Mandole R. Effect of heart failure reversal treatment as add-on therapy in patients with chronic heart failure: A randomized, open-label study. Indian Heart J [Internet]. 2017;69(3):299-304. Available from: https:// pubmed.ncbi.nlm.nih.gov/28648417/. [crossref][PubMed]
6.
Rastogi S, Chiappelli F. Hemodynamic effects of Sarvanga Swedana (Ayurvedic passive heat therapy): A pilot observational study. Ayu [Internet]. 2013;34(2):154. Available from: /pmc/articles/PMC3821243/. [crossref][PubMed]
7.
Dadoriya P, Dey YN, Sharma D, Yadav M, Wanjari MM, Gaidhani SN, et al. In- vitro anti-inflammatory and antioxidant activities of an Ayurvedic formulation- Trayodashang guggulu. J Herb Med. 2020;23:100366. [crossref]
8.
Sriwastava NK, Shreedhara CS, Aswatha Ram HN. Standardization of Ajmodadi churna, a polyherbal formulation. Pharmacognosy Res. 2010;2(2):98-101.[crossref][PubMed]

DOI and Others

DOI: 10.7860/JCDR/2023/64381.18588

Date of Submission: Mar 30, 2023
Date of Peer Review: May 20, 2023
Date of Acceptance: Aug 01, 2023
Date of Publishing: Oct 01, 2023

AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes

PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Apr 04, 2023
• Manual Googling: Jun 13, 2023
• iThenticate Software: Jul 26, 2023 (1%)

ETYMOLOGY: Author Origin

EMENDATIONS: 7

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