Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2017 | Month : October | Volume : 11 | Issue : 10 | Page : UC06 - UC09

Is Local Surgical Site Infiltration as Efficacious as Epidural Analgesia in Laparoscopic Low Anterior Resection?

Jyothi Avula, Gigi Varghese, Tunny Sebastian, Mark Ranjan Jesudason

1. Assistant Professor, Department of Anaesthesia, Christian Medical College, Vellore, Tamil Nadu, India. 2. Associate Professor, Department of Surgery and Colorectal Surgery, Christian Medical College, Vellore, Tamil Nadu, India. 3. Lecturer, Department of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India. 4. Professor and Head, Department of Surgery and Colorectal Surgery, Christian Medical College, Vellore, Tamil Nadu, India.

Correspondence Address :
Dr. Gigi Varghese,
112/2c7, New Sunset Avenue, Christian Medical College, Bagayam, Vellore-632002, Tamil Nadu, India.


Introduction: Role of epidural analgesia in laparoscopic surgery is questionable. There is paucity of data comparing local surgical site infiltration with epidural analgesia in laparoscopic colorectal resections.

Aim: To evaluate the efficacy and feasibility of local surgical site infiltration versus epidural analgesia in laparoscopic low anterior resection done for adenocarcinoma of the rectum.

Materials and Methods: This retrospective cohort study was done on 37 patients who had undergone laparoscopic low anterior resection at a single institution from January 2014 to March 2016. Patients were divided into two cohorts; Infiltration group (n=23) and Epidural group (n=14). Baseline characteristics and postoperative outcomes like number of patients requiring opioid rescue analgesia, incidence of urinary tract infection, postoperative hospital stay and overall morbidity were compared. Statistical analysis was done using SPSS software version 16.0. Mann-Whitney U test, Fischerís-exact test and Pearson Chi-square test were used to test the significance wherever necessary.

Results: The number of patients requiring rescue opioid analgesia within the first 48 hours following surgery were 5 (35.7%) in the epidural group versus 4 (17.4%) in the infiltration group (p=0.255). The incidence of urinary tract infection at the index admission was 2 (14.3%) in the epidural group versus 2 (8.7%) in the infiltration group (p=0.625). Overall morbidity calculated using Clavien Dindo classification was 8 (57.14%) and 14 (60.8%) respectively in epidural and infiltration group (p=0.836). The median (interquartile range) postoperative hospital stay for the epidural group was nine days (5-13 days) and for the infiltration group was eight days (5-15 days).

Conclusion: Surgical site infiltration is a simple technique comparable to epidural analgesia for immediate postoperative pain control in terms of efficacy and feasibility in laparoscopic low anterior resections.


Analgesia methods, Laparoscopy, Pain, Postoperative, Rectal resection

How to cite this article :

Jyothi Avula, Gigi Varghese, Tunny Sebastian, Mark Ranjan Jesudason. IS LOCAL SURGICAL SITE INFILTRATION AS EFFICACIOUS AS EPIDURAL ANALGESIA IN LAPAROSCOPIC LOW ANTERIOR RESECTION?. Journal of Clinical and Diagnostic Research [serial online] 2017 October [cited: 2018 Jan 24 ]; 11:UC06-UC09. Available from

DOI and Others

DOI: 10.7860/JCDR/2017/30356.10794

Date of Submission: May 24, 2017
Date of Peer Review: Jun 21, 2017
Date of Acceptance: Sep 25, 2017
Date of Publishing: Oct 01, 2017


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