Prevalence and Clinical Relevance of Schmorl’s Nodes on Magnetic Resonance Imaging in a Tertiary Hospital in Southern IndiaCorrespondence Address :
Dr. Devimeenal Jagannathan,
Professor and Head, Department of Radiodiagnosis, Government Kilpauk Medical College,
Chennai, Tamil Nadu-600 010, India.
Introduction: Schmorl’s Nodes (SN), which appear as defects in superior and inferior endplates of vertebrae, are commonly seen around the thoracolumbar junction. They may be asymptomatic or symptomatic. Their prevalence varies with respect to age, gender, regions involved and other associated disc or vertebral findings.
Aim: SN is quite a common finding on the Magnetic Resonance Imaging (MRI) of the spine. The purpose of the study was to evaluate the prevalence of SN in the patients who underwent MRI whole spine in the radiology department, ascertain its clinical relevance and to compare the prevalence of SN in the study population with the prevalence in rest of the Indian and global population described already in the literature.
Materials and Methods: Clinical history and MRI images of the patients who underwent whole spine MRI study in the Radiology Department during the period of 6 months from June to December 2015 were retrospectively reviewed. The prevalence of SN, their location and associated imaging findings were studied.
Results: Of the 509 patients in the study, 47 had SN at one or more levels with prevalence of 9.2%. Maximum cases were seen in the 4th decade with least cases in the extremes of age. Twenty five patients had SN at thoracic levels. Twenty five patients had SN at lumbar levels. Twenty eight patients had SN at one intervertebral disc level. Other 19 patients had SN at multiple levels. Of the total 103 SN found, 57 were seen in the superior endplates and 46 in the inferior endplates. All SNs were in central position, except for one. Twelve of the 47 patients had disc degeneration at the same level as SN. Forty two of the 47 patients (89%) with Schmorl’s nodes had associated spinal disc degenerative disease at the same or different levels. Modic type II endplate changes were demonstrated at the same level in 10 of the 47 patients with SN. Thirty eight of the 47 patients presented with history of backache. Only 9 of these patients had come with history of trauma; of these only four had wedge compression fracture at the level of SN.
Conclusion: Schmorl’s nodes in the studied South Indian population appear to show one of the lowest prevalence described on MRI, so far. Maximum number of SN occurred in the lower thoracic spine followed by the proximal lumbar spine. Schmorl’s nodes are commonly associated with degenerative disc disease of the spine, though not at the same level.
Backache, Herniation, India, Intervertebral disc, MRI
Devimeenal Jagannathan, Venkatraman Indiran, Fouzal Hithaya. PREVALENCE AND CLINICAL RELEVANCE OF SCHMORL’S NODES ON MAGNETIC RESONANCE IMAGING IN A TERTIARY HOSPITAL IN SOUTHERN INDIA. Journal of Clinical and Diagnostic Research [serial online] 2016 May [cited: 2018 Jun 20 ]; 10:TC06-TC09. Available from
Date of Submission: Feb 13, 2016
Date of Peer Review: Mar 07, 2016
Date of Acceptance: Apr 05, 2016
Date of Publishing: May 01, 2016
Financial OR OTHER COMPETING INTERESTS: None.
- Emerging Sources Citation Index (Web of Science, thomsonreuters)
- Index Copernicus ICV 2016: 132.37
- Academic Search Complete Database
- Directory of Open Access Journals (DOAJ)
- Embase & EMbiology
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Popline (reproductive health literature)