Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2016 | Month : May | Volume : 10 | Issue : 5 | Page : SC10 - SC13

Evaluation of Risk Factors Associated with First Episode Febrile Seizure

Indar Kumar Sharawat, Jitender Singh, Lesa Dawman, Amitabh Singh

1. Senior Resident, Department of Pediatric Medicine, VMMC and Safdarjung Hospital, New Delhi, India. 2. Senior Resident, Department of Pediatric Medicine, SMS Medical College, Jaipur, India. 3. Senior Resident, Department of Pediatric Medicine, AIIMS, New Delhi, India. 4. Senior Resident, Department of Pediatric Medicine, AIIMS, New Delhi, India.

Correspondence Address :
Dr. Lesa Dawman,
Room no-61, Girls Hostel no-9, AIIMS, New Delhi-110029, India.
E-mail: lesadawman@gmail.com

Abstract

Introduction: Febrile seizure (FS) is the single most common type of seizure seen in children between 6 months to 5 years of age. The purpose of our study was to identify the risk factors associated with the first episode of febrile seizures, which would help in the better management and preventive measures in children at risk for FS episodes.

Aim: To evaluate the risk factors associated with the first episode of febrile seizures in Indian children.

Materials and Methods: This was a hospital based, case control study. The purpose of this study was to identify the risk factors associated with the first FS episode in children. Seventy (70) children between age 6 months to 5 years with their first episode of FS were compared with 70 children with fever but without seizures based on various risk factors.

Results: The mean age was 24.9016.11 months in cases and 26.3416.93 months in controls. Male: female ratio was 2:1. A positive family history was found in 31.4% of first degree and 11.4% in second degree relatives. Mean maximum temperature was 102.061.1F and URI (upper respiratory infection) was most common cause of fever. Antenatal complication was significantly higher in the case group. RBC (Red Blood Cells) indices like lower mean haemoglobin, MCV (Mean Corpuscular Volume), MCH (Mean Corpuscular Haemoglobin concentration) and higher RDW (Red Cell Distribution Width) values were seen in patients. Serum sodium, Serum calcium and random blood sugar values of the cases were significantly lower than those of controls (p<0.05).

Conclusion: Our study shows that male gender, family history of febrile seizures, peak body temperature, underlying cause of fever, antenatal complications, low serum calcium, sodium, blood sugar and microcytic hypochromic anaemia are the risk factors associated with the occurrence of first episode of febrile seizure and, thus, preventive measures in removing these risk factors could lead to a decrease in incidence of FS.

Keywords

Anaemia, Children, Family history, Upper respiratory infection

How to cite this article :

Indar Kumar Sharawat, Jitender Singh, Lesa Dawman, Amitabh Singh. EVALUATION OF RISK FACTORS ASSOCIATED WITH FIRST EPISODE FEBRILE SEIZURE. Journal of Clinical and Diagnostic Research [serial online] 2016 May [cited: 2018 Jul 20 ]; 10:SC10-SC13. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2016&month=May&volume=10&issue=5&page=SC10-SC13&id=7853

DOI and Others

DOI: 10.7860/JCDR/2016/18635.7853


Date of Submission: Dec 30, 2015
Date of Peer Review: Feb 02, 2016
Date of Acceptance: Feb 23, 2016
Date of Publishing: May 01, 2016

Financial OR OTHER COMPETING INTERESTS: None.

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