Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Table of Contents - Year : 2018 | Month : August | Volume : 12 | Issue : 8 | Page : CC13 - CC16

The Effect of Vitamin D3 on Depression in Iranian Women CC13-CC16

Zeinab Mehrabani Far, Mehdi Rahnema, Hussein Qafelehbashi

Correspondence
Zeinab Mehrabanifar,
Postgraduate Student, Department of Clinical Psychology, Faculty of Education and Psychology, Zanjan Branch, Islamic Azad University, Zanjan, Iran.
E-mail: md.yar88@yahoo.com

Introduction: Depression is one of the most common psychiatric illnesses that it associated with a variety of symptoms, high rates of relapse, and many physical and psychological disorders.

Aim: To determine the effect of vitamin D3 supplements on depression in women referred to health centres in Qazvin, Iran.

Materials and Methods: Overall, 374 patients were evaluated with Beck's depression test. A total of 65 patients were included in the study after they were diagnosed with moderate and severe depression. Individuals with moderate depression were divided into two groups: 1) Cognitive Behavioural Therapy (CBT); and 2) CBT plus vitamin D3 (50,000 units of eight tablets for eight weeks). Subjects with severe depression were divided into two groups: 1) drug therapy; and 2) drug therapy plus vitamin D3. Beck's test and vitamin D3 blood sample measurements were performed before and eight weeks after intervention. Independent sample t-test was used to compare the means of control and intervention groups.

Results: Depression scores of patients in post-test stage were significantly lower than depression scores of patients in pre-test stage in all intervention methods (p<0.01). Mean depression score (11.42.5) of patients in post-test stage of intervention with CBT plus vitamin D3 was significantly lower than the depression score (14.72.7) of patients in post-test stage of intervention with CBT (p<0.05). The difference of mean depression scores in post-test stage of drug therapy (20.43.7) and drug therapy plus vitamin D3 (15.83.3) intervention methods was significant (p<0.05).

Conclusion: The use of vitamin D3 supplements can be helpful in the treatment of depression in women.