MRI in Chemotherapy induced Leukoencephalopathy: Report of Two Cases and Radiologistís Perspective TD08-TD09
Dr. Geetika Sindhwani,
Flat-12, Pocket E1, Sector 7, Rohini, New Delhi-110085, India.
Leukoencephalopathy is a progressive white matter disease primarily caused due to myelin damage by a variety of factors. Chemotherapy for oncological treatment is an uncommon but important cause of potentially reversible leukoencephalopathy. In current radiological setting, conventional and diffusion weighted MRI play a significant role in early and accurate detection of this entity. We are hereby presenting MRI evaluation of two cases of methotrexate and 5-fluorouracil induced toxic leukoencephalopathy.