Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Table of Contents - Year : 2016 | Month : July | Volume : 10 | Issue : 7 | Page : BC07 - BC09

Lipid Profile in Cardiac Syndrome X: Association with Helicobacter pylori BC07-BC09

Yousef Rasmi, Javad Zeynalzadeh, Alireza Shirpoor, Mirhossein Seyedmohammadzad, Reza Hajhosseini

Dr. Yousef Rasmi,
Professor, Cellular and Molecular Research Center, Urmia University of Medical Sciences, Urmia, Iran,
Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Introduction: Chronic inflammation caused by Helicobacter pylori (H.pylori) infection has a pathogenic role in Cardiac Syndrome X (CSX). In addition, it has shown that bacterial infection may affect blood lipids.

Aim: To assess if H.pylori affects the level of lipid profile in CSX.

Materials and Methods: Eighty-eight CSX patients and 97 healthy controls were enrolled. The Total Cholesterol (TC), Triglyceride (TG), Lipoprotein A (LP{A}), Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL), Apoprotein A1 (APOA1), and Apoprotein B (APOB) was estimated colorimetrically. In addition, the presence of IgG antibody to H.pylori was tested in plasma samples by using enzyme linked immunosorbent assay method.

Results: TC, LP{A}, LDL, APOA1 and APOB levels in CSX group were significantly higher than those of the control group (p<0.05). But, these parameters in H.pylori positive and H.pylori negative, among CSX and control groups were not significant.

Conclusion: Increased plasma level of lipid profile and H.pylori infection were associated with CSX; it seems that plasma l