Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Case report
Table of Contents - Year : 2016 | Month : June | Volume : 10 | Issue : 6 | Page : ZD12 - ZD13

Malignant Peripheral Nerve Sheath Tumor -A Rare Malignancy in Mandible ZD12-ZD13

Sumit Majumdar, Sreekanth Kotina, Nirujogi Mahesh, Divya Uppala, Singam Praveen Kumar

Dr. Nirujogi Mahesh,
Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital,
Rushikonda, Visakhapatnam-530045, India.

Malignant Peripheral Nerve Sheath Tumor (MPNST) is biologically an aggressive tumor that is usually found in the extremities, trunk and infrequently found in the head and neck area particularly in the jaws, arising from the cells allied with nerve sheath. Mandibular MPNST may either arise from a preexisting neurofibroma or develop de novo. Because of the greater variability from case to case in overall appearance both clinically and histologically, a case of MPNST of the mandible in a 25-year-old female patient is reported. The lesion was excised and immunohistological studies (S-100 & Neuron specific enolase) were conducted to confirm the neural origin.