Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Table of Contents - Year : 2016 | Month : April | Volume : 10 | Issue : 4 | Page : GC01 - GC04

-Thalassaemia and its Co-existence with Haemoglobin E and Haemoglobin S in Upper Assam Region of North Eastern India: A Hospital Based Study GC01-GC04

Anju Barhai Teli, Rumi Deori, Sidhartha Protim Saikia, Kalyani Pathak, Rita Panyang, Rashmi Rajkakati

Correspondence
Dr. Anju Barhai Teli,
Associate Professor, Department of Biochemistry, Assam Medical College & Hospital, Dibrugarh-786002, Assam, India.
E-mail: dr.anjub.t@gmail.com

Introduction: -Thalassaemias are common genetic disorders in the Indian subcontinent and its status has not been well studied in the Upper Assam region of North Eastern India.

Aim: The aim of the study was to show the prevalence of - thalassaemias and its co-existence with Haemoglobin E and Haemoglobin S in the Upper Assam region of North Eastern India.

Materials and Methods: A total of 1200 anaemic patients were investigated for - thalassaemias. Complete Blood Count (CBC) and High Performance Liquid Chromatography (HPLC) were done for screening.

Results: Out of 1200 patients screened, 5.83% -thalassaemia trait, 2.33% compound Hb E/-Thalassaemia, 1.33% -thalassaemia major and 0.42% compound Hb S/- thalassaemia were detected. A high incidence of thalassaemia is found among the people of Upper Assam region of North Eastern India.

Conclusion: The only way to prevent the disease is carrier detection and awareness among the people about it.