Variability of Standard Liver Volume by 2D Ultrasound: A Cross-sectional Study from Eastern IndiaCorrespondence Address :
Dr. Uttam Kumar Roy,
Dilip Das Sarani, Hill View Main, Paschim Bardhaman-713304, West Bengal, India.
Introduction: Liver volume estimation is an essential component prior to major hepatic surgery and liver transplantation. Liver volume is evaluated with different formulae, gold standard Computed Tomography (CT) volumetry and Magnetic Resonance Imaging (MRI). As per literature review, studies comparing ultrasonography with formula based liver volume estimation are very few. Ultrasonography is non-invasive in nature and inexpensive. It is gaining popularity among clinicians as it helps in rapid evaluation of liver volumes.
Aim: To compare variability of liver volume using 2D ultrasound with a standard well-established method based on formula derived by Johnson et al.
Materials and Methods: This was a cross-sectional study done between August-October 2020 and patients were selected by the physician from general Outpatient Department (OPD) pool and clinically screened for further biochemical studies. Participants aged 20-60 years with normal liver function test were recruited in the study. Images were taken on a Siemens Ultrasound System. Study variables included were liver volumes estimated by two methods, age, weight, height and Body Surface Area (BSA). F test was used to compare variability between liver volumes estimated by two different methods. Bivariate correlation between ultrasonography-based liver volume and different body indices was also tested.
Results: Variability comparison using F test shows no significant difference (F=1.095, df1=149, df2=149, p=0.29). Liver volumes estimated by two methods showed good correlation with each other and is significant at the 0.01 level, r=0.574. The mean difference (125 cc) in volumes between two methods were statistically significant (t=10.92, degree of freedom=149, p<0.001) and were not in agreement with each other. Body parameters were correlated with liver volume estimated by 2D ultrasound.
Conclusion: Ultrasonography is a useful tool in estimating liver volume prior to major hepatic resection. Formula based calculation of Standard Liver Volume (SLV) does not agree with USG based volume and underestimates the mean liver volume obtained by USG method.
Formula, Gold standard, Liver transplantation, Volumetry
Date of Submission: Oct 23, 2020
Date of Peer Review: Dec 21, 2020
Date of Acceptance: Jan 21, 2021
Date of Publishing: Apr 01, 2021
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? Yes
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Oct 27, 2020
• Manual Googling: Jan 20, 2021
• iThenticate Software: Jan 27, 2021 (15%)
ETYMOLOGY: Author Origin
- Emerging Sources Citation Index (Web of Science, thomsonreuters)
- Index Copernicus ICV 2017: 134.54
- Academic Search Complete Database
- Directory of Open Access Journals (DOAJ)
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Popline (reproductive health literature)