Evaluation of Bacteriological Profile and their Antimicrobial Susceptibility Pattern in Blood Stream Infections in a Multispeciality HospitalCorrespondence Address :
Miss. Mariyah Yousuf,
Department of Microbiology, School of Medical Science and Research, Sharda University, Knowledge Park 3, Greater Noida, Uttar Pradesh, India.
Introduction: Bloodstream Infections (BSIs) are one of the major cause of morbidity and mortality worldwide. To decrease the mortality from septicaemia early diagnosis and appropriate treatment of BSIs is most important. Early diagnosis of a BSI will markedly improve patient management.
Aim: To identify various pathogenic organisms causing BSIs and determine their susceptibility to various antibiotics.
Materials and Methods: A total of 1367 blood samples were received in the bacteriology laboratory for culture out of which 274 samples showed culture positivity. Among the positive cases 32 cases of Multidrug Resistance (MDR) were found. MDR cases show resistance to ≥3 classes of antibiotics. Enterobacteriaceae family showed highest MDR cases. Blood cultures were repeated for confirmation of results. Simple descriptive analysis of data was done and results presented in frequencies and percentages.
Results: Out of 274 positive samples obtained, Coagulase Negative Staphylococci (CoNS) constituted maximum proportion of isolates (66%) followed by Pseudomonas species (12%), Escherachia coli (6.2%), Klebsiella species (3.2%), Citrobacter spp. (2.9%), Staphylococcus aureus (2.9%) and Enterococcus (2.9%).
Conclusion: The present study highlighted the bacteriological aetiology of BSIs along with their antibiogram that may provide necessary information for the formulation of antibiotic policy in effective management of such cases.
Bacteremia, Blood culture, Coagulase negative staphylococcus, Multidrug resistance, Septicaemia
Date of Submission: May 03, 2020
Date of Peer Review: Jun 01, 2020
Date of Acceptance: Jul 02, 2020
Date of Publishing: Aug 01, 2020
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? Yes
• Was informed consent obtained from the subjects involved in the study? No
• For any images presented appropriate consent has been obtained from the subjects. No
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• Plagiarism X-checker: May 04, 2020
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• iThenticate Software: Jul 31, 2020 (11%)
ETYMOLOGY: Author Origin
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- Popline (reproductive health literature)