Complete Mouth Rehabilitation in a Patient with Fanconi Anaemia: A Rare Genetic Disorder
Correspondence Address :
Dr. Sonali Vedraj Sharma,
Lecturer, Department of Biomedical Dental Sciences (Oral Medicine Division), College of Dentistry, Imam Abdulrahman bin Faisal University, Dammam, Kingdom of Saudi Arabia-31441, Eastern Province, Saudi Arabia.
E-mail: svsharma@iau.edu.sa
Fanconi anaemia is a rare, progressive congenital bone marrow failure syndrome characterised by autosomal recessive inheritance and clinical manifestations, including growth retardation, bone marrow failure leading to pancytopenia, an elevated risk of malignancy, skin pigmentation, and skeletal malformations. Patients who have undergone bone marrow transplantation can be treated comprehensively in the dental clinic like other routine patients, provided their blood indices are within normal limits. Its complications include aplastic anaemia, malignancies like acute myeloid leukaemia, liver tumours, and squamous cell carcinoma, often developing post-bone marrow transplantation. Dental anomalies, altered salivary flow, and increased susceptibility to cancer necessitate early diagnosis and specialised dental care. Hereby, the authors present a case of 15-year-old male with Fanconi Anaemia who had undergone bone marrow transplantation and was treated comprehensively in a hospital setting. The present case report aimed to equip healthcare practitioners, especially dentists, with the knowledge needed for accurate diagnosis and effective management.
Autosomal recessive, Bone marrow transplantation, Hypoplasia, Periodontitis
DOI: 10.7860/JCDR/2024/67539.19141
Date of Submission: Sep 14, 2023
Date of Peer Review: Nov 03, 2023
Date of Acceptance: Jan 08, 2024
Date of Publishing: Mar 01, 2024
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Sep 15, 2023
• Manual Googling: Dec 15, 2023
• iThenticate Software: Jan 06, 2024 (5%)
ETYMOLOGY: Author Origin
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