Outcomes Assessment of Transoral Laser Microsurgery for T1 and T2 Glottic Cancer at the Ho Chi Minh City Ear-Nose-Throat Hospital
Correspondence Address :
Thuy Phan Chung Tran,
Ear-Nose-Throat Hospital at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Introduction: Transoral Laser Microsurgery (TLM) has been accepted as a major treatment modality for early glottic carcinoma (T1, T2), with well-known advantages over Radiation Therapy (RT) and open partial laryngectomy.
Aim: To evaluate the oncological outcomes in a consecutive series of early glottic carcinomas treated with TLM as a singlemodality therapy.
Materials and Methods: The study was conducted using the medical records of 32 consecutive patients who underwent TLMs and postoperative follow-ups. We only evaluated the oncological outcomes for 1-year disease-free survival and the organ preservation rate. The prognostic values of the related clinicopathological factors were evaluated using univariate analysis.
Results: Of the 32 patients, 31 were males and one was a female, with an average age of 61 years. The tumours were treated by cordectomy types IV (78.1%), Va (18.8%) and Vb (3.3%). The voice outcomes were assessed using the Voice Handicap Index scale, which showed that 8 patients had normal voices and 22 had mild changes. Only 2 had moderateto- severe voice changes. The mean hospitalization period was 4.4 days (range 3-7 days). For resection margins, as reported by the pathologist, 31 cases (96.9%) had negative margins and 1 case (3.1%) had a positive margin.
Conclusion: Laser surgery has very good oncological outcomes for T1 and T2 glottic cancer with the highly proportion of negative margins and the voice outcomes is normal or mild changed.
Cancer, ENT hospital, Ho Chi Minh City, Glottic, Outcome Assessment, Transoral Laser Microsurgery
Date of Submission: Apr 07, 2018
Date of Peer Review: May 30, 2018
Date of Acceptance: Jun 04, 2018
Date of Publishing: Jun 15, 2018
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