Clinical Study for Efficacy of Different Diagnostic Tools for the Diagnosis of Acute AppendicitisCorrespondence Address :
Dr. Ranendra Hajong,
Associate Professor, Department of General surgery, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong-793018, Meghalaya, India.
Introduction: Acute Appendicitis (AA) is one of the most common causes of surgical abdominal pain and can be confused with other diseases due to atypical presentations of the disease. So, to aid in the diagnosis the various scoring systems and radiochemical investigations are in use such as Modified Alvarado Score (MAS), Ultrasonography (USG) of abdomen, Computed Tomography (CT) scan of abdomen and serum bilirubin levels.
Aim: To study the diagnostic efficacy of MAS, USG of abdomen, CT scan of abdomen and serum bilirubin level for the diagnosis of AA.
Materials and Methods: This was a prospective observational study conducted in the North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India. A total of 72 patients with the clinical diagnosis of AA participated in the study. The patients were subjected to MAS, USG of abdomen; serum bilirubin level and Contrast-Enhanced Computed Tomography (CECT) scan on admission. Sensitivity, specificity, positive predictive value and negative predictive value for each test were found. Final diagnosis was confirmed histopathologically. Descriptive statistics data were calculated using SPSS version 22.0.
Results: Sensitivity was highest for USG 42 (80.77%) out of 52. Specificity was highest for CT scan 18 (90%) out of 20, when target sign was found positive in the patient and also in cases of serum bilirubin 18 (90%) out of 20 when the patient had perforated appendicitis. Otherwise the overall diagnostic accuracy of USG was the highest 47 (65.28%) of 72.
Conclusion: Diagnosis of AA is still challenging as the overall sensitivity or specificity of scoring system as well as radiochemical analysis is still very poor.
Modified alvarado score, Serum bilirubin, Ultrasonography of abdomen
Ranendra Hajong, Narang Naku, Malaya Ranjan Dhal, Manash Pratim Boruah, Ojing Komut, Arup Jyoti Baruah, et al.. CLINICAL STUDY FOR EFFICACY OF DIFFERENT DIAGNOSTIC TOOLS FOR THE DIAGNOSIS OF ACUTE APPENDICITIS. Journal of Clinical and Diagnostic Research [serial online] 2018 April [cited: 2018 Oct 22 ]; 12:PC01-PC04. Available from
Date of Submission: Sep 15, 2017
Date of Peer Review: Nov 24, 2017
Date of Acceptance: Dec 26, 2017
Date of Publishing: Apr 01, 2018
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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