Unusual Presentation of Light Chain Deposition Disease: A Case ReportCorrespondence Address :
Dr. Disha Arora,
House Number 6, Block Number 12, First Floor, West Patel Nagar, New Delhi – 110008 India.
Light Chain Deposition Disease (LCDD) is a rare disease characterized by deposition of monoclonal non-amyloid light chains in multiple organs. We report an unusual histologic manifestation of LCDD in a 55-year-old female patient, who presented with nephrotic syndrome and an increased serum creatinine. This case of LCDD had features of cast nephropathy on biopsy which is diagnostic of myeloma kidney, when the patient was clinically asymptomatic. Serum electrophoresis showed no abnormal band. There was no other evidence of a B-cell clonal disorder or amyloidosis. Following chemotherapy, improvement in renal function correlated with a reduction in circulating light-chain levels.
Cast nephropathy, Myeloma kidney, Nephrotic syndrome
Disha Arora, Mayank Uppal, Vindu Amitabh, Usha Agrawal. UNUSUAL PRESENTATION OF LIGHT CHAIN DEPOSITION DISEASE:
A CASE REPORT. Journal of Clinical and Diagnostic Research [serial online] 2016 May [cited: 2018 Oct 17 ]; 10:ED08-ED09. Available from
Date of Submission: Dec 15, 2015
Date of Peer Review: Jan 22, 2016
Date of Acceptance: Feb 29, 2016
Date of Publishing: May 01, 2016
Financial OR OTHER COMPETING INTERESTS: None.
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