Case report
Diabetic Mastopathy Mimicking Malignancy: A Surgical Perspective on Diagnosis and Management
Correspondence Address :
Dr. Imran Thariq Ajmal,
Professor, Department of General Surgery, Chettinad Hospital and Research Institute, Kelambakkam, Tamil Nadu, India.
E-mail: drnandy97@gmail.com
Diabetic Mastopathy (DMP) is an uncommon benign fibroinflammatory condition of the breast, predominantly seen in individuals with long-standing diabetes mellitus. It often mimics malignancy on clinical and radiological examination, leading to diagnostic uncertainty. DMP accounts for 0.5-13.5% of all benign breast lesions. Here, authors present the case of a 48-year-old postmenopausal female who presented with complaints of serous, cheesy discharge of minimal quantity from the right nipple, intermittently for the past 10 years, along with pain over the right breast for the last four weeks. Clinical evaluation revealed a firm, tender subareolar mass with nipple-areola distortion and cheesy discharge. Imaging via sonomammography revealed a Breast Imaging Reporting and Data System 3 (BIRADS 3) hypoechoic lesion with cystic areas and ductal dilatation. A wide local excision, including the removal of the distorted nipple-areola complex, was performed. Gross and histopathological examination showed fibrocystic changes with dense fibrous stroma, lymphoplasmacytic infiltration and giant cells, consistent with DMP. Close clinical follow-up is essential. Heightened clinical awareness and individualised treatment strategies can help minimise unnecessary surgeries while ensuring patient safety and reassurance.
Benign breast disease, Case report, Lymphoplasmacytic infiltration, Recurrence, Wide local excision
DOI: 10.7860/JCDR/2025/79135.21450
Date of Submission: Mar 07, 2025
Date of Peer Review: Jun 24, 2025
Date of Acceptance: Aug 11, 2025
Date of Publishing: Sep 01, 2025
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Mar 21, 2025
• Manual Googling: Aug 07, 2025
• iThenticate Software: Aug 09, 2025 (4%)
ETYMOLOGY: Author Origin
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