The Spectrum of Clinical Manifestations of Serious Human Parvovirus B19 Infection in Children without any Underlying Diseases- A Case Series
SR06-SR07
Correspondence
Dr. Subham Bhattacharya,
Assistant Professor, Department of Haematology, NRSMCH, Kolkata, West Bengal, India.
E-mail: drsubham@rediffmail.com
Human Parvovirus B19 causes mild to life-threatening illnesses, especially in immunosuppressed individuals. In the immunocompetent individuals, the severe spectrum of clinical manifestations of the virus infection is not widely known. This case series presents the spectrum of clinical manifestations of serious Parvovirus B19 infection in children without any chronic haematological or immunodeficiency disease. The series comprises a total of 12 children who tested positive for Parvovirus Immunoglobulin M (IgM) antibody, and their age range was between 1-12 years. Fever, fatigue, and arthritis were the most common manifestations. Pure red cell aplasia, the specific manifestation of Parvovirus infection, was seen only in one-third of the patients. All the children were treated with Intravenous Immunoglobulin (IVIG) along with supportive therapy. All except one had a successful recovery.