Synchronous Odontogenic Cysts in Mandible ZD10-ZD12
Dr. Sunitha Carnelio,
Professor, Department of Oral and Maxillofacial Pathology, Manipal College of Dental Sciences, MAHE, Manipal-576104, Karnataka, India.
Odontogenic cysts are derived from odontogenic apparatus which may develop before or after the formation of tooth. Most of these are developmental in origin. However, non-odontogenic cysts also exist in the jaw. Among the odontogenic cysts the most prevalent are periapical cyst followed by dentigerous and Odontogenic Keratocyst (OKC). OKC was also termed as Keratocystic Odontogenic Tumour (KCOT), well-known for its aggressive behaviour, varied origin, debated development and tendency to recur has been the focus of much research and discussion since four decades. It arises either from epithelial rests of the dental lamina or the tooth primordium and is generally aggressive and invasive, while dentigerous cysts are common odontogenic cysts that are related to the crown of the impacted tooth and known to arise from reduced enamel epithelium. It is rare to find both these entities occurring simultaneously in the same patient. Multiple OKC are generally associated with nevoid basal cell carcinoma syndrome, and accounts to the mutation in the PTCH, a tumour suppressor gene. However, this case reports a non-syndromic variant. A 13-year-old female patient with multiple cysts in the jaw that were evaluated, diagnosed and treated adequately based on clinical, radiographic and histopathological examination has been discussed.