Assessment of Health-Related Quality of Life in Patients with Type II Diabetes Mellitus: A Population-Based Study at a Tertiary Hospital LC44-LC51
Trung Quang Vo,
Department of Pharmacy Administration, Faculty of Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City,
Ho Chi Minh City-700000, Vietnam.
Introduction: The rising incidence of diabetes, worldwide, has necessitated an evaluation of diabetes impacts on Health- Related Quality of Life (HRQoL). The recognition of risk factors that lower HRQoL can improve HRQoL in patients with Type 2 Diabetes Mellitus (T2DM).
Aim: To explore the impact of T2DM on HRQoL among adolescents/adults treated at a tertiary hospital in southern Vietnam.
Materials and Methods: This cross-sectional study was conducted from Julyâ€“September 2017 at District 9 Hospital, Ho Chi Minh City, Vietnam. In total, 286 patients with T2DM underwent face-to-face interviews and completed the Diabetes- 39 (D-39) questionnaire (previously evaluated for reliability). Each subscale score was summed and transformed into a scale of 0â€“100. HRQoL differences were evaluated by Mann-Whitney and Kruskal-Wallis nonparametric tests.
Results: The Cronbachâ€™s alpha coefficients were all over 0.80 and showed acceptable high internal consistency. The lowest Cronbachâ€™s alpha was obtained for â€˜Anxiety and worryâ€™ (0.81) and the highest for â€˜Diabetes controlâ€™ and â€˜Sexual behaviourâ€™ (0.93). The Intraclass Correlation Coefficient (ICC) ranged from 0.80 for â€˜Anxiety and worryâ€™ to 0.93 for â€˜Sexual behaviourâ€™ and agreed well for all subscales and the D-39 total score. The median D-39 total score was 35.0 (scale 0â€“100). Patients prescribed insulin or who had a family history of diabetes scored higher on â€˜Diabetes controlâ€™ and â€˜Social behaviourâ€™ and the D-39 total score. Multiple linear regression analyses revealed that having an urban area residence, no income and high BMI predicted a lower impact of diabetes on HRQoL scores. Conversely, unemployment correlated with higher scores for â€˜Energy and mobilityâ€™ and the total HRQoL, while family history had a higher impact on â€˜Anxiety and worryâ€™ and â€˜Social burdenâ€™. The presence of complications was associated with a higher â€˜Energy and mobilityâ€™ score.
Conclusion: The Diabetes-39 Vietnamese version used in our study had acceptable reliability for evaluating HRQoL in patients with T2DM. The â€˜Energy and mobilityâ€™ and â€˜Anxiety and worryâ€™ subscales were highly impacted by T2DM, indicating a need to address physical function and patient psychology. The independent predictors are useful additions to diabetes care programs suitable for individuals.