Sodium Valproate Induced Alopecia: A Case Series FR01-FR02
Dr. Shalini Adiga,
Professor and Head, Department of Pharmacology, KMC, Manipal, Udupi, Karnataka, India.
Drug induced alopecia may range from a barely detectable shedding to an irreversible baldness. Alopecia associated with valproate is a dose-dependent and reversible side effect. We hereby report, three cases of alopecia that occurred in patients who received sodium valproate for various neurological conditions. In all three cases, long term exposure of valproate therapy led to the development of alopecia which eventually resolved after dose reduction or discontinuation. The Naranjo’s causality assessment scale indicated valproate as the probable cause of the alopecia in all our patients.