Hepatosplenic T Cell Lymphoma in an Immunocompetent Female Diagnosed using Flow Cytometry: A Rare Clinical Entity ED15-ED16
Dr. Pranav Dorwal,
Department of Pathology & Laboratory Medicine, UG Floor, Clinical Labs
Medanta The Medicity, Sector 38, Gurgaon-122001, Haryana, India.
Hepatosplenic T-cell lymphoma is a rare haematopoietic malignancy that comprises less than 1% of Non-Hodgkin lymphomas. We are reporting a case of a 26-year-old female, who presented with pallor, weight loss, jaundice, pancytopenia and hepatosplenomegaly. The bone marrow examination showed infiltration by lymphoid cells. These cells on flow cytometric evaluation showed the phenotype of hepatosplenic T cell lymphoma. The cells were positive for CD3, CD8, CD56 and TCR ?d and negative for CD5, CD4, CD8, CD16, CD57, TCRaß along with B cell markers. This case is reported for being a rare clinical entity and its presence in an immunocompetent female making it rarer.