Thyroid Stimulating Hormone (TSH) Level as a Possible Indicator of Pre-eclampsia 1542-1543
Associate Professor, Dept. of Physiology,
Sri Siddhartha Medical College,
Tumkur, Karnataka, India â€“ 572102.
Background: Pre-Eclampsia is characterized by hypertension and proteinuria. There is a high incidence of thyroid dysfunction during pregnancy resulting in adverse maternal and fetal effects. Therefore, we intended to evaluate the influence of pre-eclampsia on thyroid hormone levels.
Methods: Twenty five (25) pregnant women who developed preeclamplsia and an equal number of age matched, parity matched and gestation age matched normal pregnant women were taken for the study. Blood samples collected were estimated for T3, T4 and TSH which was measured using CLIA system Results: 64% offspring of the pre-eclampsia subjects had birth weight <2.5kg and the values were highly significant. T3 and T4 levels were within the normal limits and there was significant increase in TSH levels in pre eclampsia subjects.
Conclusion: In the present study the pre-eclampsia showed elevated TSH levels with a risk of low birth weight babies. Increase TSH levels could be used as a predictor of Pre-eclampsia.