Acute Ocular Side Effects of Topiramate 1082-1085
Ritesh Singla (M.S.)
Asst. Professor, Department of Ophthalmology
Adesh Medical College & Hospitall
Purpose: To evaluate the acute ocular side effects of Topiramate in patients of migraine.
Design: Retrospective study.
Materials and Methods: 296 patients of migraine of all ages and of either sex, who were being treated with Topiramate from January 2010 to January 2011 by the neurologist, were retrospectively studied for severe ocular side effects.
Results: Four patients of different ages and of either sex reportedwith signs of shallow anterior chamber , bilateral acute myopia and angle closure glaucoma of varying severity. All four patients responded well to conservative treatment and immediate cessation of Topiramate therapy.
Conclusions: Topiramate which is recently being used quite frequently and effectively in the treatment of migraine has rare but potential side effects in the form of bilateral acute angle closure glaucoma which can be effectively managed with prompt stoppage of Topiramate therapy and conservative management.