Prescribing Trends in Depression – A Drug Utilization Study Done at a Tertiary Healthcare Centre 573-577
c/o Dr. Amita Ray
B-2, Father Muller Quarters,
Phone No. 09916821079
Introduction: Depression is one of the most prevalent forms of mental illnesses.The â€˜Global Burden of Diseaseâ€™ study showed that depressive disorders were the fourth leading cause of burden among all the diseases. Depression accounted for 4.46% of the total DALYs (Disability Adjusted Life Years) and 12.1% of the YLDs (Years Lived with Disability) in 2002, as opposed to 3.7% of the DALYs and 10.7% of the YLDs in 1990.With the increase in the number of patients, there has been an increase in the number and the type of antidepressants which are available to the psychiatrists and other clinicians. This study was aimed to assess the current prescribing practice.
Materials and Methods: The data which was collected included information on the age, sex and the drug prescribed, including the group, subgroup, trade name, dosage and distribution in 50 outpatients who attended the psychiatry OPD.
Results: In this study, 82% of the subjects were females whereas 18% were males. Most of the patients were in the age group of 41-60 years followed by the 21â€“40 years age group, the above 60 years age group and the below 21 years age group. Most of the patients were prescribed selective serotonin reuptake inhibitors (SSRIs), followed by serotonin nor-epinephrine reuptake inhibitors (SNRIs) and tricyclic antidepressants (TCAs). The most prescribed SSRI was Escitalopram.
Conclusion: In this study on depression, most of the subjects were females. Most of the patients were in the age group of 41â€“60 yrs. By and large, the newer groups of drugs, namely the SSRIs and the SNRIs seem to have replaced the older group, namely the TCAs. This seems to be in accordance with other research findings especially considering the fewer side effects of the newer group of drugs and the prolonged therapy which was needed to combat depression effectively.