Tuberculosis and Acute Deep Vein Thrombosis in a Paediatric Case
Published: June 1, 2015 | DOI: https://doi.org/10.7860/JCDR/2015/.6078
Jayesh Sangani, Satarupa Mukherjee, Soumyadeep Biswas, Tarun Chaudhuri, Gautam Ghosh
1. Junior Resident, Department of Pediatrics, B.R.Singh Hospital & Centre for Medical Education and Research Kolkata, India.
2. Senior Resident, Department of Pediatrics, B.R.Singh Hospital & Centre for Medical Education and Research Kolkata, India.
3. Senior Resident, Department of Pediatrics, B.R.Singh Hospital & Centre for Medical Education and Research Kolkata, India.
4. Chief Specialist II, Department of Pediatrics, B.R.Singh Hospital & Centre for Medical Education and Research Kolkata, India.
5. Consultant Pediatrician, Department of Pediatrics, B.R.Singh Hospital & Centre for Medical Education and Research Kolkata, India.
Correspondence Address :
Dr. Satarupa Mukherjee,
Senior Resident, Department of Pediatrics, B.R.Singh Hospital & Centre for Medical Education and Research Kolkata-700014, India.
Email: satarupamukherjee2003@gmail.com
Abstract
Deep vein thrombosis (DVT) may be associated with tuberculosis infection. DVT in tuberculosis (TB) is implicated to the release of inflammatory cytokines, decrease synthesis of anti-coagulant proteins and increased fibrinogen levels. Drugs may also predispose to the hyper-coaguability. DVT may correlate with the severity of mycobacterium infection. We report a case of DVT in an 11-year-old child with sputum positive pulmonary tuberculosis. The patient was put on low molecular weight heparin after Doppler documentation of thrombosis of left femoral vein. She was then put on oral warfarin with complete resolution of the thrombosis. A clinician should be aware of this rare but dangerous association of tuberculosis and must not delay in early diagnosis and intervention.
Keywords
Hyper-coaguability, Pulmonary tuberculosis