Year :
2021
| Month :
March
| Volume :
15
| Issue :
3
| Page :
OD06 - OD08
Full Version
Concurrent Occurrence of Cytomegalovirus
Retinitis and Oesophagitis in an
Immunocompromised Male Patient
Published: March 1, 2021 | DOI: https://doi.org/10.7860/JCDR/2021/47220.14684
Aishwarya Dilip Ghule, Sourya Acharya, Samarth Shukla, Yogendra Oke, Sree Kartik Pratapa
1. Junior Resident, Department of Medicine, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India.
2. Professor, Department of Medicine, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India.
3. Professor, Department of Pathology, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India.
4. Professor, Department of Ophthalmology, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India.
5. Junior Resident, Department of Medicine, Datta Meghe Institute of Medical ScIences, Wardha, Maharashtra, India.
Correspondence Address :
Dr. Sourya Acharya,
Professor, Department of Medicine, Datta Meghe Institute of Medical Sciences,
Wardha-442004, Maharashtra, India.
E-mail: souryaacharya74@gmail.com
Abstract
Cytomegalovirus (CMV) is a double-stranded Deoxyribonucleic Acid (DNA) virus which causes severe disease in immunocompromised individuals. Chorioretinitis accounts for 80-90% of CMV infection in patients with Acquired Immunodeficiency Syndrome (AIDS) having CD4 (Cluster of Differentiation) counts <50 μ/mL, and rarely in those with CD4 counts more than 100 μ/mL. In developing countries, CMV infection is known to cause blindness in 5-25% of Human Immunodeficiency Virus (HIV) infected individuals. After colitis, oesophagitis is the most common Gastrointestinal Tract (GIT) manifestation of CMV in immunocompromised individuals. In immunocompetent individuals the disease associated with CMV is often self-limiting. So, authors presented a case report of 40-year-old HIV infected male, with CD4 count of 75 μ/mL, having complaints of dysphagia and concomitant blindness. On the basis of an array of investigations, he was diagnosed as having CMV retinitis with oesophagitis. He had a predictable outcome after treatment with Gancyclovir (GCV). Thus, in immunocompromised individuals, especially with a CD4 count <100 μ/mL, surveillance of oesophagitis and retinitis with endoscopic and fundoscopic interventions, respectively, must be done. This can help in improving life expectancy in such individuals.
Keywords
Acquired immunodeficiency syndrome, Blindness, Colitis, Dysphagia
DOI: 10.7860/JCDR/2021/47220.14684
Date of Submission: Oct 15, 2020
Date of Peer Review: Dec 23, 2020
Date of Acceptance: Jan 19, 2021
Date of Publishing: Mar 01, 2021
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Oct 16, 2020
• Manual Googling: Jan 05, 2021
• iThenticate Software: Feb 03, 2021 (11%)
ETYMOLOGY: Author Origin
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