Year :
2019
| Month :
June
| Volume :
13
| Issue :
6
| Page :
YC05 - YC09
Full Version
Relationship of Respiratory Muscle Strength and Walking Distance with Pulmonary Function, Quality of Life and Nitric Oxide in Chronic Obstructive Pulmonary Disease Patients
Published: June 1, 2019 | DOI: https://doi.org/10.7860/JCDR/2019/39998.12959
Jirakrit Leelarungrayub, Rungthip Puntumetakul, Thanyaluck Sriboonreung, Yothin Pothasak, Jakkrit Klaphajone
1. Associate Professor, Department of Physical Therapy, Faculty of Associated Medical Sciences, Mung Chiang Mai, Chiang Mai, Thailand.
2. Associate Professor, Research Centre in Back, Neck, Other Joint Pain and Human Performance (BNOJPH), Khon Kaen University, Khon Kaen, Thailand.
3. Associate Professor, Department of Physical Therapy, Faculty of Associated Medical Sciences, Mung Chiang Mai, Chiang Mai, Thailand.
4. Department of Physical Therapy, Faculty of Associated Medical Sciences, Mung Chiang Mai, Chiang Mai, Thailand.
5. Associate Professor, Department of Rehabilitation Medicine, Faculty of Medicine, Mung Chiang Mai, Chiang Mai, Thailand.
Correspondence Address :
Dr. Jirakrit Leelarungrayub,
110 Sripum, Mung Chiang Mai, Chiang Mai, Thailand.
E-mail: donrawee.leela@cmu.ac.th
Abstract
Introduction: Respiratory muscle strength and walking distance have been associated with the severity of disease and is used in prescribing rehabilitation programs for persons with Chronic Obstructive Pulmonary Disease (COPD).
Aim: To evaluate the correlation between respiratory muscle strength and walking distance with pulmonary function, plasma Nitric Oxide (NO) levels and Quality of Life (QoL) score in persons with stable COPD.
Materials and Methods: The present cross-sectional study was conducted in 35 participants with moderate severity, stable COPD. Physical outcomes such as respiratory muscle strength (PImax), walking distance {6-minute walking distance (6MWD)} and pulmonary function {Forced Vital Capacity (FVC), Forced Expiratory Volume at one second (FEV1), and FEV1/FVC ratio} were evaluated. In addition, a total Clinical COPD Questionnaire (CCQ) and plasma NO levels were determined. The Pearson’s correlation test was analysed statistically.
Results: The present results revealed that the participants had a significantly positive correlation on PImax with FVC (r=0.624, p<0.001), FEV1 (r=0.539, p<0.001), and NO (r=0.510, p<0.001), whereas, the 6MWD correlated positively to FVC (r=0.390, p=0.018), FEV1 (r=0.548, p<0.001), FEV1/FVC ratio (r=0.55, p<0.001) and NO (p=0.416, p=0.013), but negatively to the total QoL score (r=-0.579, p<0.001).
Conclusion: This preliminary study demonstrates that respiratory muscle strength and walking performance possibly relate to pulmonary function and plasma NO among persons having COPD with moderate severity.
Keywords
Maximal inspiratory muscle pressure, Respiratory muscle strength, Six-minute walking distance
DOI: 10.7860/JCDR/2019/39998.12959
Date of Submission: Oct 17, 2018
Date of Peer Review: Nov 27, 2018
Date of Acceptance: May 10, 2019
Date of Publishing: Jun 01, 2019
FINANCIAL OR OTHER COMPETING INTERESTS: As declared above.
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