Mesenchymal Lesion in an Adolescent Girl-A Rare Case Report
Published: March 1, 2018 | DOI: https://doi.org/10.7860/JCDR/2018/32412.11247
R Manibarathi, R Narmadha, AP Rajesh Nataraj, J Pavithra, Bharathi Vidhya Jayanthi
1. Postgraduate, Department of Pathology, Madras Medical College, Chennai, Tamil Nadu, India.
2. Assistant Professor, Department of Pathology, Madras Medical College, Chennai, Tamil Nadu, India.
3. Assistant Professor, Department of Pathology, Madras Medical College, Chennai, Tamil Nadu, India.
4. Tutor, Department of Pathology, Madras Medical College, Chennai, Tamil Nadu, India.
5. Director and Professor, Department of Pathology, Madras Medical College, Chennai, Tamil Nadu, India.
Correspondence Address :
Dr. R Narmadha,
15, 2nd Cross Street, Mahalakshmi Nagar, Adambakam, Chennai-600088, Tamil Nadu, India.
E-mail: narmi_ram@yahoo.co.in
Abstract
Rhabdomyosarcoma (RMS) comprises 3% of all childhood malignancy. Commonly it involves head and neck, extremity and genitourinary systems. Pure primary RMS of breast is a rare malignacy. Here, we present a case of adolescent girl presented with breast lump which was initially treated as benign lesion with excision. Again she presented with recurrent mass which was operated and microscopically showed features of small blue round cell tumour which has lead to many diagnostic confusions both clinically and histopathologically. Immunohistochemistry (IHC) with strong nuclear myogenin positivity in >50% of tumour cells confirms the diagnosis of primary mammary RMS. Postoperative period was uneventful.
Keywords
Adolescent age, Myogenin, Rhabdomyosarcoma of breast