Year :
2017
| Month :
August
| Volume :
11
| Issue :
8
| Page :
OD05 - OD06
Full Version
Meropenem Induced Hypokalemia
Published: August 1, 2017 | DOI: https://doi.org/10.7860/JCDR/2017/27584.10387
T V Anuhya, Raviraj Acharya, Sharath Madhyastha, Ram Bhat, Veena Nayak
1. Postgraduate, Department of Pharmacology, KMC, Manipal University, Udupi, Karnataka, India.
2. Professor, Department of Medicine, KMC, Manipal University, Udupi, Karnataka, India.
3. Professor, Department of Medicine, KMC, Manipal University, Udupi, Karnataka, India.
4. Professor, Department of Medicine, KMC, Manipal University, Udupi, Karnataka, India.
5. Associate Professor, Department of Pharmacology, KMC, Manipal University, Udupi, Karnataka, India.
Correspondence Address :
Dr. Veena Nayak,
Associate Professor, Department of Pharmacology, KMC, Manipal University, Udupi-576104, Karnataka, India.
E-mail: veena.nayak@manipal.edu
Abstract
Meropenam, a beta-lactam antibiotic has been used for severe infections of skin, tissue, intra- abdominal and urogenital infections in hospitalized patients. The common adverse effects reported are diarrhoea, vomiting, rashes and hypersensitivity reactions. Here we report two cases of meropenam induced hypokalemia, wherein, meropenam was prescribed for cellulitis and urinary tract infection in the first and second case respectively. Hypokalemia can manifest as muscular weakness, fatigue, muscle cramps, constipation, ileus, flaccid paralysis, hyporeflexia, hypercapnia, tetany, rhabdomyolysis or respiratory failure. Hence, it is necessary to make physicians aware of such an adverse effect which can develop with meropenam.
Keywords
Antibacterial agents, Beta-lactam antibiotics, Hypokalemia, Infections
DOI: 10.7860/JCDR/2017/27584.10387
Date of Submission: Feb 15, 2017
Date of Peer Review: Mar 10, 2017
Date of Acceptance: May 05, 2017
Date of Publishing: Aug 01, 2017
FINANCIAL OR OTHER COMPETING INTERESTS: None.
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