Dual Outcomes: Live Pregnancy Amidst Partial Hydatidiform Mole

1. Junior Resident, Department of Radiology, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India. 2. Head, Department of Radiology, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India. 3. Assistant Professor, Department of Radiology, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India. 4. Junior Resident, Department of Radiology, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India. 5. Professor, Department of Radiology, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India.

Abstract

Gestational Trophoblastic Disease (GTD) is a group of cancers that can metastasise to distant sites. Molar pregnancy, a rare and challenging condition, is characterised by Complete Hydatidiform Moles (CHM) occurring when one sperm fertilises an empty ovum, resulting in the absence of maternal chromosomes. Partial Hydatidiform Mole (PHM) is triploid and is often detected early in gestation. In one out of every 20,000 to 100,000 pregnancies, along with a CHM or PHM, a normal co-twin may emerge. Here, we present a similar case of a young primigravida presenting with a live foetus and a concomitant partial mole. In this case, a 22-year-old primigravida female presented with lower abdominal pain, nausea, and vomiting for the last two weeks. She was advised to undergo an antenatal scan at 24 weeks of gestation, which showed a dichorionic diamniotic pregnancy with a single live foetus and a molar placenta. Later, she was put on conservative management and followed up with subsequent delivery of a premature live baby and expulsion of a molar placenta. Twin pregnancies with a normal foetus and a CHM are rare but can lead to live deliveries with no appreciable rise in the probability of malignant transformation of CHM. It is critical to differentiate these pregnancies from other disorders such as Placental Mesenchymal Dysplasia (PMD) and PHM, which also involve a foetus and a cystic placenta. Suction dilation and curettage are the preferred treatments for women with a hydatidiform mole to maintain fertility.

Grape-like vesicles, Hydatidiform mole, Prematurity, Twin pregnancy