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Dr Bhanu K Bhakhri

"The Journal of Clinical and Diagnostic Research (JCDR) has been in operation since almost a decade. It has contributed a huge number of peer reviewed articles, across a spectrum of medical disciplines, to the medical literature.
Its wide based indexing and open access publications attracts many authors as well as readers
For authors, the manuscripts can be uploaded online through an easily navigable portal, on other hand, reviewers appreciate the systematic handling of all manuscripts. The way JCDR has emerged as an effective medium for publishing wide array of observations in Indian context, I wish the editorial team success in their endeavour"



Dr Bhanu K Bhakhri
Faculty, Pediatric Medicine
Super Speciality Paediatric Hospital and Post Graduate Teaching Institute, Noida
On Sep 2018



Dr Mohan Z Mani

"Thank you very much for having published my article in record time.I would like to compliment you and your entire staff for your promptness, courtesy, and willingness to be customer friendly, which is quite unusual.I was given your reference by a colleague in pathology,and was able to directly phone your editorial office for clarifications.I would particularly like to thank the publication managers and the Assistant Editor who were following up my article. I would also like to thank you for adjusting the money I paid initially into payment for my modified article,and refunding the balance.
I wish all success to your journal and look forward to sending you any suitable similar article in future"



Dr Mohan Z Mani,
Professor & Head,
Department of Dematolgy,
Believers Church Medical College,
Thiruvalla, Kerala
On Sep 2018



Prof. Somashekhar Nimbalkar

"Over the last few years, we have published our research regularly in Journal of Clinical and Diagnostic Research. Having published in more than 20 high impact journals over the last five years including several high impact ones and reviewing articles for even more journals across my fields of interest, we value our published work in JCDR for their high standards in publishing scientific articles. The ease of submission, the rapid reviews in under a month, the high quality of their reviewers and keen attention to the final process of proofs and publication, ensure that there are no mistakes in the final article. We have been asked clarifications on several occasions and have been happy to provide them and it exemplifies the commitment to quality of the team at JCDR."



Prof. Somashekhar Nimbalkar
Head, Department of Pediatrics, Pramukhswami Medical College, Karamsad
Chairman, Research Group, Charutar Arogya Mandal, Karamsad
National Joint Coordinator - Advanced IAP NNF NRP Program
Ex-Member, Governing Body, National Neonatology Forum, New Delhi
Ex-President - National Neonatology Forum Gujarat State Chapter
Department of Pediatrics, Pramukhswami Medical College, Karamsad, Anand, Gujarat.
On Sep 2018



Dr. Kalyani R

"Journal of Clinical and Diagnostic Research is at present a well-known Indian originated scientific journal which started with a humble beginning. I have been associated with this journal since many years. I appreciate the Editor, Dr. Hemant Jain, for his constant effort in bringing up this journal to the present status right from the scratch. The journal is multidisciplinary. It encourages in publishing the scientific articles from postgraduates and also the beginners who start their career. At the same time the journal also caters for the high quality articles from specialty and super-specialty researchers. Hence it provides a platform for the scientist and researchers to publish. The other aspect of it is, the readers get the information regarding the most recent developments in science which can be used for teaching, research, treating patients and to some extent take preventive measures against certain diseases. The journal is contributing immensely to the society at national and international level."



Dr Kalyani R
Professor and Head
Department of Pathology
Sri Devaraj Urs Medical College
Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka
On Sep 2018



Dr. Saumya Navit

"As a peer-reviewed journal, the Journal of Clinical and Diagnostic Research provides an opportunity to researchers, scientists and budding professionals to explore the developments in the field of medicine and dentistry and their varied specialities, thus extending our view on biological diversities of living species in relation to medicine.
‘Knowledge is treasure of a wise man.’ The free access of this journal provides an immense scope of learning for the both the old and the young in field of medicine and dentistry as well. The multidisciplinary nature of the journal makes it a better platform to absorb all that is being researched and developed. The publication process is systematic and professional. Online submission, publication and peer reviewing makes it a user-friendly journal.
As an experienced dentist and an academician, I proudly recommend this journal to the dental fraternity as a good quality open access platform for rapid communication of their cutting-edge research progress and discovery.
I wish JCDR a great success and I hope that journal will soar higher with the passing time."



Dr Saumya Navit
Professor and Head
Department of Pediatric Dentistry
Saraswati Dental College
Lucknow
On Sep 2018



Dr. Arunava Biswas

"My sincere attachment with JCDR as an author as well as reviewer is a learning experience . Their systematic approach in publication of article in various categories is really praiseworthy.
Their prompt and timely response to review's query and the manner in which they have set the reviewing process helps in extracting the best possible scientific writings for publication.
It's a honour and pride to be a part of the JCDR team. My very best wishes to JCDR and hope it will sparkle up above the sky as a high indexed journal in near future."



Dr. Arunava Biswas
MD, DM (Clinical Pharmacology)
Assistant Professor
Department of Pharmacology
Calcutta National Medical College & Hospital , Kolkata



Dr. C.S. Ramesh Babu
" Journal of Clinical and Diagnostic Research (JCDR) is a multi-specialty medical and dental journal publishing high quality research articles in almost all branches of medicine. The quality of printing of figures and tables is excellent and comparable to any International journal. An added advantage is nominal publication charges and monthly issue of the journal and more chances of an article being accepted for publication. Moreover being a multi-specialty journal an article concerning a particular specialty has a wider reach of readers of other related specialties also. As an author and reviewer for several years I find this Journal most suitable and highly recommend this Journal."
Best regards,
C.S. Ramesh Babu,
Associate Professor of Anatomy,
Muzaffarnagar Medical College,
Muzaffarnagar.
On Aug 2018



Dr. Arundhathi. S
"Journal of Clinical and Diagnostic Research (JCDR) is a reputed peer reviewed journal and is constantly involved in publishing high quality research articles related to medicine. Its been a great pleasure to be associated with this esteemed journal as a reviewer and as an author for a couple of years. The editorial board consists of many dedicated and reputed experts as its members and they are doing an appreciable work in guiding budding researchers. JCDR is doing a commendable job in scientific research by promoting excellent quality research & review articles and case reports & series. The reviewers provide appropriate suggestions that improve the quality of articles. I strongly recommend my fraternity to encourage JCDR by contributing their valuable research work in this widely accepted, user friendly journal. I hope my collaboration with JCDR will continue for a long time".



Dr. Arundhathi. S
MBBS, MD (Pathology),
Sanjay Gandhi institute of trauma and orthopedics,
Bengaluru.
On Aug 2018



Dr. Mamta Gupta,
"It gives me great pleasure to be associated with JCDR, since last 2-3 years. Since then I have authored, co-authored and reviewed about 25 articles in JCDR. I thank JCDR for giving me an opportunity to improve my own skills as an author and a reviewer.
It 's a multispecialty journal, publishing high quality articles. It gives a platform to the authors to publish their research work which can be available for everyone across the globe to read. The best thing about JCDR is that the full articles of all medical specialties are available as pdf/html for reading free of cost or without institutional subscription, which is not there for other journals. For those who have problem in writing manuscript or do statistical work, JCDR comes for their rescue.
The journal has a monthly publication and the articles are published quite fast. In time compared to other journals. The on-line first publication is also a great advantage and facility to review one's own articles before going to print. The response to any query and permission if required, is quite fast; this is quite commendable. I have a very good experience about seeking quick permission for quoting a photograph (Fig.) from a JCDR article for my chapter authored in an E book. I never thought it would be so easy. No hassles.
Reviewing articles is no less a pain staking process and requires in depth perception, knowledge about the topic for review. It requires time and concentration, yet I enjoy doing it. The JCDR website especially for the reviewers is quite user friendly. My suggestions for improving the journal is, more strict review process, so that only high quality articles are published. I find a a good number of articles in Obst. Gynae, hence, a new journal for this specialty titled JCDR-OG can be started. May be a bimonthly or quarterly publication to begin with. Only selected articles should find a place in it.
An yearly reward for the best article authored can also incentivize the authors. Though the process of finding the best article will be not be very easy. I do not know how reviewing process can be improved. If an article is being reviewed by two reviewers, then opinion of one can be communicated to the other or the final opinion of the editor can be communicated to the reviewer if requested for. This will help one’s reviewing skills.
My best wishes to Dr. Hemant Jain and all the editorial staff of JCDR for their untiring efforts to bring out this journal. I strongly recommend medical fraternity to publish their valuable research work in this esteemed journal, JCDR".



Dr. Mamta Gupta
Consultant
(Ex HOD Obs &Gynae, Hindu Rao Hospital and associated NDMC Medical College, Delhi)
Aug 2018



Dr. Rajendra Kumar Ghritlaharey

"I wish to thank Dr. Hemant Jain, Editor-in-Chief Journal of Clinical and Diagnostic Research (JCDR), for asking me to write up few words.
Writing is the representation of language in a textual medium i e; into the words and sentences on paper. Quality medical manuscript writing in particular, demands not only a high-quality research, but also requires accurate and concise communication of findings and conclusions, with adherence to particular journal guidelines. In medical field whether working in teaching, private, or in corporate institution, everyone wants to excel in his / her own field and get recognised by making manuscripts publication.


Authors are the souls of any journal, and deserve much respect. To publish a journal manuscripts are needed from authors. Authors have a great responsibility for producing facts of their work in terms of number and results truthfully and an individual honesty is expected from authors in this regards. Both ways its true "No authors-No manuscripts-No journals" and "No journals–No manuscripts–No authors". Reviewing a manuscript is also a very responsible and important task of any peer-reviewed journal and to be taken seriously. It needs knowledge on the subject, sincerity, honesty and determination. Although the process of reviewing a manuscript is a time consuming task butit is expected to give one's best remarks within the time frame of the journal.
Salient features of the JCDR: It is a biomedical, multidisciplinary (including all medical and dental specialities), e-journal, with wide scope and extensive author support. At the same time, a free text of manuscript is available in HTML and PDF format. There is fast growing authorship and readership with JCDR as this can be judged by the number of articles published in it i e; in Feb 2007 of its first issue, it contained 5 articles only, and now in its recent volume published in April 2011, it contained 67 manuscripts. This e-journal is fulfilling the commitments and objectives sincerely, (as stated by Editor-in-chief in his preface to first edition) i e; to encourage physicians through the internet, especially from the developing countries who witness a spectrum of disease and acquire a wealth of knowledge to publish their experiences to benefit the medical community in patients care. I also feel that many of us have work of substance, newer ideas, adequate clinical materials but poor in medical writing and hesitation to submit the work and need help. JCDR provides authors help in this regards.
Timely publication of journal: Publication of manuscripts and bringing out the issue in time is one of the positive aspects of JCDR and is possible with strong support team in terms of peer reviewers, proof reading, language check, computer operators, etc. This is one of the great reasons for authors to submit their work with JCDR. Another best part of JCDR is "Online first Publications" facilities available for the authors. This facility not only provides the prompt publications of the manuscripts but at the same time also early availability of the manuscripts for the readers.
Indexation and online availability: Indexation transforms the journal in some sense from its local ownership to the worldwide professional community and to the public.JCDR is indexed with Embase & EMbiology, Google Scholar, Index Copernicus, Chemical Abstracts Service, Journal seek Database, Indian Science Abstracts, to name few of them. Manuscriptspublished in JCDR are available on major search engines ie; google, yahoo, msn.
In the era of fast growing newer technologies, and in computer and internet friendly environment the manuscripts preparation, submission, review, revision, etc and all can be done and checked with a click from all corer of the world, at any time. Of course there is always a scope for improvement in every field and none is perfect. To progress, one needs to identify the areas of one's weakness and to strengthen them.
It is well said that "happy beginning is half done" and it fits perfectly with JCDR. It has grown considerably and I feel it has already grown up from its infancy to adolescence, achieving the status of standard online e-journal form Indian continent since its inception in Feb 2007. This had been made possible due to the efforts and the hard work put in it. The way the JCDR is improving with every new volume, with good quality original manuscripts, makes it a quality journal for readers. I must thank and congratulate Dr Hemant Jain, Editor-in-Chief JCDR and his team for their sincere efforts, dedication, and determination for making JCDR a fast growing journal.
Every one of us: authors, reviewers, editors, and publisher are responsible for enhancing the stature of the journal. I wish for a great success for JCDR."



Thanking you
With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
Associate Professor,
Department of Paediatric Surgery, Gandhi Medical College & Associated
Kamla Nehru & Hamidia Hospitals Bhopal, Madhya Pradesh 462 001 (India)
E-mail: drrajendrak1@rediffmail.com
On May 11,2011



Dr. Shankar P.R.

"On looking back through my Gmail archives after being requested by the journal to write a short editorial about my experiences of publishing with the Journal of Clinical and Diagnostic Research (JCDR), I came across an e-mail from Dr. Hemant Jain, Editor, in March 2007, which introduced the new electronic journal. The main features of the journal which were outlined in the e-mail were extensive author support, cash rewards, the peer review process, and other salient features of the journal.
Over a span of over four years, we (I and my colleagues) have published around 25 articles in the journal. In this editorial, I plan to briefly discuss my experiences of publishing with JCDR and the strengths of the journal and to finally address the areas for improvement.
My experiences of publishing with JCDR: Overall, my experiences of publishing withJCDR have been positive. The best point about the journal is that it responds to queries from the author. This may seem to be simple and not too much to ask for, but unfortunately, many journals in the subcontinent and from many developing countries do not respond or they respond with a long delay to the queries from the authors 1. The reasons could be many, including lack of optimal secretarial and other support. Another problem with many journals is the slowness of the review process. Editorial processing and peer review can take anywhere between a year to two years with some journals. Also, some journals do not keep the contributors informed about the progress of the review process. Due to the long review process, the articles can lose their relevance and topicality. A major benefit with JCDR is the timeliness and promptness of its response. In Dr Jain's e-mail which was sent to me in 2007, before the introduction of the Pre-publishing system, he had stated that he had received my submission and that he would get back to me within seven days and he did!
Most of the manuscripts are published within 3 to 4 months of their submission if they are found to be suitable after the review process. JCDR is published bimonthly and the accepted articles were usually published in the next issue. Recently, due to the increased volume of the submissions, the review process has become slower and it ?? Section can take from 4 to 6 months for the articles to be reviewed. The journal has an extensive author support system and it has recently introduced a paid expedited review process. The journal also mentions the average time for processing the manuscript under different submission systems - regular submission and expedited review.
Strengths of the journal: The journal has an online first facility in which the accepted manuscripts may be published on the website before being included in a regular issue of the journal. This cuts down the time between their acceptance and the publication. The journal is indexed in many databases, though not in PubMed. The editorial board should now take steps to index the journal in PubMed. The journal has a system of notifying readers through e-mail when a new issue is released. Also, the articles are available in both the HTML and the PDF formats. I especially like the new and colorful page format of the journal. Also, the access statistics of the articles are available. The prepublication and the manuscript tracking system are also helpful for the authors.
Areas for improvement: In certain cases, I felt that the peer review process of the manuscripts was not up to international standards and that it should be strengthened. Also, the number of manuscripts in an issue is high and it may be difficult for readers to go through all of them. The journal can consider tightening of the peer review process and increasing the quality standards for the acceptance of the manuscripts. I faced occasional problems with the online manuscript submission (Pre-publishing) system, which have to be addressed.
Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal as an outlet for their work."



Dr. P. Ravi Shankar
KIST Medical College, P.O. Box 14142, Kathmandu, Nepal.
E-mail: ravi.dr.shankar@gmail.com
On April 2011

Important Notice

Original article / research
Year : 2024 | Month : June | Volume : 18 | Issue : 6 | Page : VD01 - VD04 Full Version

Ayurvedic Management of Mansik Avasaad (Depressive Disorder): A Case Report

Published: June 1, 2024 | DOI: https://doi.org/10.7860/JCDR/2024/68917.19495

Annya Gautam, Madhvi Jain, Vinod Ade, Shweta Parwe

1. PG Scholar, Department of Panchakarma, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India. 2. PG Scholar, Department of Panchakarma, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India. 3. Professor, Department of Panchakarma, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India. 4. Professor and Head, Department of Panchakarma, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India.

Correspondence Address :
Dr. Annya Gautam,
Mahatma Gandhi Ayurved Medical College Hospital and Research Center, Salod, (Sawangi), Wardha-442001, Maharashtra, India.
E-mail: ananyagautam68@gmail.com

Abstract

Depression is a significant mental health issue that will impact most people’s lives in one way or another. It can diminish someone’s quality of life and have a negative impact on their ability to work and maintain relationships. The worst case scenario for severe depression is suicide. There still exists a societal stigma around depression due to its prevalence, suffering, dysfunction, morbidity, and financial burden. Currently, 80% of individuals with depression are not receiving any treatment. Historical ayurvedic literature sporadically mentions depression as both an illness (manasika vyadhi) and an emotional state. The purpose of the study was to assess the comprehensive Ayurvedic management strategy for depressive disorder. Here the authors discusses a case that involves a 23-year-old male patient presenting with chief complaints of poor concentration, weight loss, and social withdrawal. He was treated using ayurvedic principles such as Sarvang Snehan, Baspa Sweda, Shirodhara, and Shamana Chikitsa. After 15 days, the patient’s symptoms were re-assessed, resulting in a satisfactory outcome and an overall improvement in his life. The combination of snehan, swedana, shirodhara, and Shaman chikitsa significantly facilitated the management of depression.

Keywords

Ayurveda, Depressive disorder, Satvajaya chikitsa, Shirodhara

Case Report
In the current case, a 23-year-old male patient visited the outpatient department with chief complaint of weight loss (8 kg), lethargy, poor appetite, lack of interaction with family and friends, and difficulty concentrating on work for the past two years. The patient became increasingly reclusive and lost interest in social interactions. As his symptoms worsened day by day, he stopped eating. In terms of personal history, the patient was vegetarian, walks for 20 to 30 minutes daily, and experiences difficulty in sleeping due to overthinking. The patient was not addicted to any substances, and there was no personal or family history of illness.

Clinical examination revealed stable vital signs with a normal temperature, a pulse rate of 84 beats per minute, and blood pressure of 110/70 mmHg. Additionally, the respiratory rate was observed to be 18 breaths per minute. Systemic examinations, including those of the respiratory system, central nervous system, cardiovascular system, gastrointestinal system, and locomotor system, all yielded normal results.

As the patient’s health deteriorated, his parents encouraged him to seek Ayurvedic treatment for management. Upon examination and history taking, it was discovered that the patient exhibited maximum Avsada (depression) symptoms along with some signs of a restricted eating disorder. His assessment resulted in a Hamilton Depression Rating Scale (HDRS) score of 25. Subsequently, the patient was advised to be admitted to the hospital for Satvajaya Chikitsa and Ayurvedic treatments.

The patient presented with a range of complaints, including weight loss, loss of appetite, poor concentration, premature ejaculation, and anhedonia, persisting for two years. Associated complaints such as fatigue, insomnia, low mood, and weakness were also noted, complicating the clinical presentation. The duration and overlapping nature of these complaints suggest a complex health challenge affecting the patient’s overall well-being. A comprehensive assessment and tailored treatment plan addressing each complaint are crucial to alleviate symptoms and enhance the patient’s quality of life.

The Ashtavidha pariksha, or eight-fold examination, is a fundamental diagnostic method in Ayurveda aimed at evaluating various aspects of an individual’s health. This examination involves assessing the pulse to determine the balance of Vata and Pitta doshas, as well as examining stool and urine to ascertain their normalcy based on the individual’s Prakriti (constitution).

The appearance of the tongue indicates the state of Saam dosha, while speech clarity reflects mental clarity and coherence. Touch perception reveals sensitivity to temperature and texture. Vision assessment considers visual acuity and clarity. Lastly, the overall appearance is evaluated to determine if it aligns with the individual’s Madhyam prakriti (1).

The Dashvidha pariksha, or Ten-fold Examination, is a comprehensive diagnostic approach in Ayurveda that evaluates various facets of an individual’s health (1). In this case, the patient’s prakruti is identified as Vata-Pitta, while vikruti indicates imbalances in rakta (blood), rasa (bodily fluids), and sukravaha (reproductive system). The Samhanan reveals a weekly compact body structure. Pramana measurements show the patient to be underweight with a Body Mass Index (BMI) of 14.0 kg/m2 before treatment, which improved slightly to 14.6 kg/m2 after 15 days of treatment, with a weight increase from 43 kg to 45 kg. The patient exhibits Madhyama satmya, indicating moderate adaptability, and Avarasatva, suggesting average mental strength. Ahara shakti is deemed average, while Vyayam shakti is low.

Considering the patient’s Yuvaavastha (youthful age), a treatment plan involving Panchakarma and Shamana therapies was devised to address their condition comprehensively and restore balance to their overall health and well-being.

The overall treatment plan: External therapy for the patient involves a structured protocol consisting of two main procedures conducted over a span of 10 days each. The first procedure, Sarvang snehana, employs Bala Ashwagandha oil for a full-body oleation massage. This therapy aims to nourish tissues, alleviate muscular tension, and promote overall relaxation and rejuvenation. The second procedure, Shirodhara, utilises a blend of Brahmi oil and Amla oil. During Shirodhara, a continuous stream of warm herbal oil is gently poured onto the forehead, targeting the mind and nervous system to induce profound relaxation, mental clarity, and emotional balance.

Shamana chikitsa, constituting internal medicine, outlines a structured treatment plan aimed at alleviating the patient’s symptoms over a period of 15 days. This regimen comprises five medicinal interventions tailored to address specific health concerns. Ashwandharishta, administered at a dosage of 15 mL twice daily with lukewarm water after food, aims to promote vitality and overall well-being. Cap. Herbokam, taken as one capsule twice daily after meals, contributes to enhancing the body’s resilience and vigor. Vanari kalpa, consumed at a dosage of two teaspoons twice daily with milk, supports reproductive health and vitality. Syrup Shankhapushpi, ingested at 10 mL twice daily after meals, aids in improving cognitive function and reducing mental stress. Finally, Avipatikar churna, consumed at five grams twice daily before meals with lukewarm water, helps in alleviating digestive discomfort and promoting gastrointestinal health.

This comprehensive approach to internal medicine targets multiple aspects of the patient’s health, aiming for symptom relief and overall well-being within the specified timeframe. The prescribed yoga asanas and meditation routine offer a holistic approach to improving the patient’s physical and mental well-being. This daily regimen comprises five key practices, starting with Savasana for deep relaxation, followed by Shishuasana to release back tension. Anulom vilom breathing balances life force energy, while Om japa fosters mental calmness. Listening to the Maha Mrityunnjaya Mantra enhances spiritual nourishment. Together, these practices aim to promote relaxation, mental clarity, and spiritual growth, contributing to the patient’s overall health and wellness. The prescribed pathya regimen emphasises the importance of maintaining a balanced lifestyle and diet conducive to overall well-being. It includes ensuring adequate sleep of eight hours at night and incorporating ghee and foods with Madhura Rasa (sweet taste) into the diet, such as easily digestible options like moong dal, khichadi, and seasonal fruits. Conversely, the apathya regimen advises against consuming hot and spicy foods, excessive salt, fried foods, sour fruits, and fermented items like curd and pickles. It also cautions against night awakening and excessive daytime sleeping.

Follow-up and outcome: The patient was hospitalised for the first 12 days of treatment, during which Panchakarma procedures were performed along with Satvavajaya chikitsa and shaman chikitsa. The patient was taught to assess and quantify worry and their relaxed state of mind. Mantra uchharan with adequate yoga guidance and daily assignments were given to keep the patient involved. Giving the patient a reward for finishing the previous task motivates them to do the next one more successfully. Encourage them every day by sharing stories of people who have overcome similar obstacles to reach optimism in their lives. Urge the patient to commit to memory the perfect representation of God and to stand up for themselves when they feel like giving up. These were used for the modulation of Satvavajaya chikitsa. During this period, the patient showed improvement in worry, relaxed state of mind, worthlessness, lack of interest, and interacting with others. After 15 days of follow-up, the patient’s condition was much improved. The patient felt rejuvenated and good. Their mental state, communication, and socialisation improved.

On the 15th-day follow-up, the patient’s treatment regimen includes three medications aimed at supporting their continued recovery.

Tablet Liv 52 DS is prescribed to be taken twice daily before meals. Tablet Vigomax Forte is to be taken twice daily after meals with milk. Additionally, Syrup Memorin is recommended twice daily after meals to support cognitive function and memory. With a duration of 15 days, this follow-up plan aims to sustain the progress made and further contribute to the patient’s overall well-being.

Before treatment, the patient reported spending approximately three to four hours daily in a state of relaxation, which significantly improved to 12 to 16 hours per day after intervention. Conversely, worrying consumed the majority of their day, totaling 12 to 14 hours before treatment and significantly decreasing to only one to two hours per day post-treatment. Sleep duration also notably increased from a mere three to four hours to a more restorative eight hours per night. Furthermore, the HDRS score dropped from 25 before treatment to seven after the intervention, indicating a marked improvement in depressive symptoms (Table/Fig 1). These changes collectively suggest a positive response to the treatment regimen, with significant enhancements in relaxation, worry reduction, sleep quality, and depressive symptoms observed within a 15-day period.
Discussion
Emotions are fundamental aspects of human existence, or manasika bhava. However, a person may be experiencing mental illness if their feelings, thoughts, or behaviour frequently cause them distress or interfere with their daily activities and those around them. Although it is estimated that upto one in five persons have some sort of mental illness, there is still stigma and discrimination associated with it. In most cases, depression is an untreated illness that is not widely acknowledged or treated. When it comes to matters of health, Ayurveda places special emphasis on the mind and its diseases. Each and every Ayurvedic classic discusses both physical diseases and their psychological effects. Ayurvedic descriptions of psychiatric diseases from thousands of years ago are still applicable today (2).

Depression affects individuals of all ages, from all backgrounds, and throughout the world. It causes mental suffering and affects people’s capacity to perform even simple tasks, sometimes with painful repercussions on family and societal interactions. The worst-case scenario for depression is suicide. It results from disturbances in the body’s essential elements, including tridosha, triguna, rasa dhathu, manovaha srotas, satwa, jnanendriya and karmendriya, agni, and ojas. Yoga, in the form of dynamic exercise and pranayama, can be practiced as a counter-agent and prophylactic to the medicine and dietary patterns that improve cognitive function.The moral codes of conduct (achara rasayana), sadvritta, and ritucharya (seasonal regimens) described in our science can all be put into practice as preventative measures (3).

Similar studies (4),(5),(6) have consistently shown that satvavajya chikitsa, oral medicines, shirodhara, takradhara, and other external panchakarma procedures play a major role in treating depression (Table/Fig 2). The primary medhya and balya characteristics of the oral drugs employed in these studies demonstrate that medication alone is ineffective in treating depression. Counseling also plays a significant role in improving the patient’s condition. As a result, this study demonstrates highly significant results in patients with depression. Counseling helps patients improve their mental toughness and increases the effort that patients’ relatives put forth on their behalf. All of these subjects fall under Satvavavjaya. The primary effect of the entire treatment plan in the current case study was positivity, which the patient was encouraged to emphasise with the use of panchakarma, yoga, meditation, and medicine. After panchakarma procedures, the following oral medications were administered: Ashwagandharista, Syrup Shankhapushpi, Avipatikar churna, and Vanari kalpa throughout the treatment period. The patient had gradual and sustained clinical improvement. Mode of Action of Sarvang Abhyanga: Abhyanga is a traditional Ayurvedic practice that has demonstrated effectiveness in the treatment and prevention of disease. It has been described as an external method of administering oil or unctuous substances to the body by rubbing, whether they are medicinal or not, with the goal of restoring the balance of Dosha by acting both locally and systemically (7).

Bala ashwagandha taila is an herbal remedy that mostly contains bala, ashwagandha, and laksha. It is prescribed for arthritis and to strengthen the muscles, etc. It also possesses antipyretic, antispasmodic, antiseptic, and analgesic qualities. Ashwagandha has immune-boosting, antistress, anti-inflammatory, and antioxidant effects (8).

Mode of action of Shirodhara: Shirodhara is a combination of the Sanskrit words shiro (head) and dhara (to flow). Shirodhara is a type of independent snehana technique in which liquids are gently poured over the forehead. It is traditionally recommended for a number of neurobehavioral and psychosomatic diseases (9).

The well-known Ayurvedic herb brahmi, also known by its botanical name Bacopa monnieri, is used to boost mental acuity, focus, and memory. It is a combination of the Vata and Kapha doshas. Due to its ushna virya, or hot potency, it calms excessive Kapha and Vata dosha. Brahmi is helpful for all psychiatric disorders like depression, anxiety, OCD, etc. It supports the heart, blood vessels, and nerves (10). Amla balances the vata, pitta, and kapha dosha. It has antiaging and rejuvenating properties.

Mode of action of Ashwagandharista: A fermented remedy known as ashwagandharishta is used to treat neurological and behavioral ailments. Additionally, it is administered as a general tonic. As one of the key ingredients, ashwagandha exhibits properties such as jivaniya, medhya, rasayana, anti-stress, adaptogenic, hypnotic, anxiolytic, sedative, balya, and brimhana. It can be used to treat chronic neurological, musculoskeletal, psychological, and emaciation-related illnesses (11).

Mode of action of capsule Herbokam: The triple-in-one Herbokam plus capsule contains three herbal extracts from Brahmi, Jatamansi, and Ashwagandha. Adults who use these pills report feeling more relaxed, getting better sleep, reducing anxiety, and waking up feeling rejuvenated. This natural remedy revives the nerve system and soothes the mind to encourage restful sleep, making it useful for stress-related exhaustion and insomnia. This capsule helps to revitalise and rejuvenate the body (12).

Mode of action of Vanari Kalp: It is a Sandu Pharmaceuticals-exclusive medication. It mostly consists of kapikacchu and kalpa, which are created with the aid of sugar. It claims that it can aid in restoring virility and potency. It enhances physical stamina, lowers stress, encourages well-being, and is an effective aphrodisiac (13).

Mode of action of Syrup Shankhapushpi: One of the most significant Medhya Rasayana medications in Ayurveda. The herb is astringent and bitter, and its use enhances the balance and vitiation in the Kaphavata-pitta doshas. Herbalists theorise that Shankhpushpi soothes nerves by controlling the body’s production of cortisol and adrenaline, two stress chemicals. This medication exhibits antidepressant, antidiabetic, cardioprotective, sedative, antioxidant, neuroprotective, and hypolipidemic effects. It boosts memory and learning abilities. The hypotensive qualities of the flowers and leaves are used to treat anxiety neurosis (14).

Mode of action of Avipattikar Churna: Avipattikar Churna is used to treat gastrointestinal issues. Constipation and gastritis can both be effectively treated with it. It contains potent therapeutic herbs that help reduce the symptoms of certain disorders and promote the digestive tract’s normal operations. It also functions as an appetiser and is therefore frequently administered to patients who are experiencing loss of appetite as a result of various illnesses such as depression, gastric ulcers, and any chronic crippling ailment (15).

Mode of action of LIV52 DS: It increases the liver’s and spleen’s functional effectiveness while protecting the liver’s histological architecture and having positive effects on the liver’s glycogen and serum proteins. It has strong antioxidant properties due to how it affects lipid peroxidation (16).

Mode of action of tablet Vigomax Forte: The Vigomax Forte Tablet improves erectile and sexual function. Ashwagandha is effective in preventing early ejaculation. Kapikacchu has aphrodisiac properties, boosts vigor, and treats neurological disorders. Safed Musli boosts libido and physical endurance. Vata is balanced by erand mula (17).

Mode of action of syrup Memorin: It is one of the best Ayurvedic herbs used to treat fever, tension, and anxiety while enhancing memory, intelligence, speech, immunity, and digestion (18).
Conclusion
Ayurveda offers an integrated approach to effectively address psychiatric disorders by restoring dosha balance through Yukti Vyapashraya chikitsa along with Satvavajaya techniques such as yoga and counselling play a crucial role in treating these types of cases. Counselling sessions for both the patient and their family contribute to enhancing overall well-being. However, further research is needed to validate these findings and gain international recognition.
Reference
1.
Rohit S, Hetal A, Prajapati PK. Astasthana Pariksha-A diagnostic method of Yogaratnakara and its clinical importance. Global Journal of Research on Medicinal Plants & Indigenous Medicine. 2012;1(5):186.
2.
Bloom DE, Cafiero E, Jané-Llopis E, Abrahams-Gessel S, Bloom LR, Fathima S, et al. The global economic burden of noncommunicable diseases. Program on the Global Demography of Aging; 2012 Jan. Available from: https://www.hsph.harvard.edu/pgda/wp-content/uploads/sites/1288/2013/10/PGDA_WP_87.pdf.
3.
Madhavi AR, Savitha HP. Depression-an ayurvedic outlook. J Ayu Holistic Med. 2017;5(2):12-23.
4.
Tubaki BR, Chandake S, Sarhyal A. Ayurveda management of major depressive disorder: A case study. Journal of Ayurveda and Integrative Medicine. 2021;12:378-83. Doi: 10.1016/j.jaim.2021.03.012. Epub 20 May 2021 [PubMed: 34024690] [PubMed Central: PMC8186000].   [CrossRef]  [PubMed]
5.
Goyal P, Mishra D. Ayurvedic management on Manoavsada (depression): Case report. Int J Ayu Pharm Res. 2022;10(5):69-63.   [CrossRef]
6.
Thasni M, Jithesh M, Brinu JA. Ayurvedic management of moderate depressive disorder-A case report. International Journal of Ayurveda and Pharma Research. 2022;10(4):37-43.   [CrossRef]
7.
Sharma N, Kumar A, Panja AK. Abhyanga: A conceptual review. World Journal of Pharmaceutical Research. 2015;4 (11):585-92.
8.
Raut RG. Analytical study of balaashwagandha taila. Int J Ayur Alli Sci. 2014;3:171- 76. Available from: http://indianmedicine.eldoc.ub.rug.nl/id/eprint/69147.
9.
Moharana H, Mahapatra AK, Maharana L, kumar Singh S. Therapeutic efficacy and mechanism of action of ayurvedic shirodhara: An evidence based review. World Journal of Ayurveda Shirodhara. 2017;2(1):131-39.
10.
Roodenrys S, Booth D, Bulzomi S, Phipps A, Micallef C, Smoker J. Chronic effects of Brahmi (Bacopa monnieri) on human memory. Neuropsychopharmacol. 2002;27(2):279-81.   [CrossRef]  [PubMed]
11.
Acharya RS. Clinical indications of Ashwagandharishta an experiential and scientific view. Journal of Ayurveda and Integrated Medical Sciences. 2022;7(1):116-18.
12.
Herbules. HERBOKAM Plus Capsules: A natural tranquilizer, promotes deep & revitalizing sleep. Nagpur, Maharashtra, India. Herbules. Available from: https:// www.herbules.in/herbokam-plus.html.
13.
Sandu. Navi Mubai, India. Available from: https://sandu.in/product/sandu-vanari-kalpa-ayurvedic-herbalmedicine-for-men-health-improve-strength-200-g/. Cited date of access: 10/08/2022.
14.
Jalwal P, Singh B, Dahiya J, Khokhara S. A comprehensive review on shankhpushpi a morning glory. The Pharma Innovation. 2016;5(1, Part A):14.
15.
Patil S, Shah S. Preparation, quality control and stability studies of avipattikar churna. Journal of Drug Delivery and Therapeutics. 2019;9(3-s):531-36.
16.
Maity SG, Mandal AK. A clinical comparative study to evaluate the efficacy and safety of Liv. 52 DS tablets in Non-Alcoholic Steatohepatitis (NASH). World J Pharm Res. 2015;4(7):388-414.
17.
Singh A. Evaluation of clinical efficacy of the Vigomax Forte Tablet in male sexual dysfunction. Journal of Ayurveda and Integrated Medical Sciences. 2023;8(4):01-08.   [CrossRef]
18.
Ayurmed Info. Memorin syrup uses, doses, ingredients, side effects. Easy Ayurveda. 2023. Available from: https://www.ayurmedinfo.com/2018/09/01/memorin-syrup/.
DOI and Others
DOI: 10.7860/JCDR/2024/68917.19495

Date of Submission: Dec 13, 2023
Date of Peer Review: Feb 03, 2024
Date of Acceptance: Apr 11, 2024
Date of Publishing: Jun 01, 2024

AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval Obtained for this study? Yes
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. Yes

PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Dec 06, 2023
• Manual Googling: Feb 15, 2024
• iThenticate Software: Apr 09, 2024 (7%)

ETYMOLOGY: Author Origin

EMENDATIONS: 7
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