Mycobacterial Infection after Cosmetic Procedure with Botulinum Toxin A
Published: April 1, 2015 | DOI: https://doi.org/10.7860/JCDR/2015/.5756
Marcela Saeb-Lima, Gerardo-Victor Solis-Arreola, Angel Fernandez-Flores
1. Consultant Dermatologist, Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán,
Hospital Angeles Lomas, Centro Medico ABC, Mexico City, Mexico.
2. Dermatology, Private Practice.
3. Dermatopathologist, Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain.
Correspondence Address :
Dr. Angel Fernandez-Flores,
Servicio de Anatomía Patologica, Hospital El Bierzo, Medicos sin Fronteras 7, 24411, Ponferrada, Spain.
E-mail: dermatopathonline@gmail.com
Abstract
We report a case of mycobacterial infection at the sites of previous injections of botulinum toxin A in a 45-year-old woman. She presented with erythematous, swollen, warm, and tender plaques and nodules at the points of injection from which a biopsy was taken, demonstrating a deep dermal and hypodermal abscessified epithelioid granulomatous inflammatory infiltrate in which some acid-fast bacilli were identified with Ziehl-Neelsen and Fite-Faraco stains. The lesion was first treated with clarithromycin plus azithromycin, to which rifampicin was later added. A good therapeutic response was obtained.
Keywords
Botox, Iatrogenic infection, Mycobacteria, Tuberculosis