Solitary Plasmacytoma of Skull: A
Rare Cytological Diagnosis
Published: August 1, 2013 | DOI: https://doi.org/10.7860/JCDR/2013/.3259
Manmeet Kaur Gill, Manisha Makkar, Satinder Pal Singh Bains
1. Senior Resident, Department of Pathology, SR in UCMS/GTBH, Delhi, India.
2. Assistant Professor, Department of Pathology, Adesh Medical College, Bathinda, Punjab, India.
3. Senior Resident, Department of Surgery, SR in Lok Nayak Hospital, Delhi, India.
Correspondence Address :
Dr. Manmeet Kaur Gill,
H.N. 22265/A, Shant Nagar, Bathinda, Punjab, India.
Phone: 09876610985, E-mail: drmanmeet16@hotmail.com
Abstract
Solitary Plasmacytoma of the Skull (SPS) is very rare and only 35 cases have been reported in the English literature. It remains controversial whether a solitary plasmacytoma of the skull is essentially identical with a Solitary Plasmacytoma of Bone (SPB) or not. A solitary plasmacytoma of bone, which includes a solitary plasmacytoma of the skull, is characterized by a radiologically solitary bone lesion, neoplastic plasma cells in the biopsy specimen, fewer than 5% plasma cells in bone marrow, less than 2.0 g/dl monoclonal protein in the serum when it is present and a negative urine test for Bence Jones protein (monoclonal light chain). A solitary plasmacytoma of bone tends to disseminate or progress to multiple myeloma, even as long as 7-23 years after its presentation.
Keywords
Fine needle aspiration cytology, Solitary plasmacytoma, Skull