Year :
2020
| Month :
November
| Volume :
14
| Issue :
11
| Page :
QC05 - QC08
Full Version
Relationship between Maternal and Perinatal Outcome with High Vaginal Swab Culture: A Cross-sectional Study
Published: November 1, 2020 | DOI: https://doi.org/10.7860/JCDR/2020/45330.14235
Charu Mahajan, Devyani Misra, Mariyam Faruqi, Rajkumar Mishra
1. Assistant Professor, Department of Obstetrics and Gynaecology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
2. Assistant Professor, Department of Obstetrics and Gynaecology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
3. Senior Resident, Department of Obstetrics and Gynaecology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
4. Senior Resident, Department of Obstetrics and Gynaecology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Correspondence Address :
Dr. Mariyam Faruqi,
B-1/4, Sector-D, Aliganj, Lucknow-226024, Uttar Pradesh, India.
E-mail: faruqimariyam@gmail.com
Abstract
Introduction: Most of the pregnancies progress normally but unfortunately, few are prone to developing complications. Some antenatal and intra-partum conditions place the mother and the developing foetus or both at risk for complications and infections which undoubtedly play a major role in the same. Vaginal microbiome composition changes during pregnancy. This change is believed to inhibit pathogen growth through secretion of bacteriocins such as lactic acid that maintain acidic pH. Disturbed vaginal environment is associated with complications of pregnancy.
Aim: To find the relationship between the microbiological study of High Vaginal Swab (HVS) in pregnancy at term with the maternal and foetal outcome.
Materials and Methods: This cross-sectional study was conducted on 200 women who underwent vaginal swab culture during routine prenatal check-up from July 2019 to January 2020, in a hospital in Lucknow, Uttar Pradesh, India. The maternal and perinatal outcome and their relation with microbiological study of HVS were studied. Statistical analysis was done using Statistical Package for the Social Sciences (SPSS) version 11.5. Chi-square test was used for comparison of data for statistical significance. For descriptive statistics percentage, mean and Standard Deviation (SD) was calculated.
Results: E.coli (18%) was the most common organism isolated from HVS cultures in this study. Maternal complications, rate of Lower Segment Caesarean Section (LSCS), low APGAR scores (Appearance, Pulse, Grimace, Activity and Respiration), need for neonatal resuscitation and Neonatal Intensive Care Unit (NICU) admission were more in the culture positive group.
Conclusion: The study suggests that the abnormal vaginal microbiota is associated with adverse pregnancy outcomes. HVS cultures are simple and non-invasive screening tool which should be used as a routine procedure in all antenatal patients for preventing complications and improving the foeto-maternal outcome.
Keywords
Maternal morbidity, Neonatal intensive care unit admission, Perinatal morbidity, Puerperial pyrexia, Respiratory distress syndrome, Sepsis
DOI: 10.7860/JCDR/2020/45330.14235
Date of Submission: Jun 04, 2020
Date of Peer Review: Jun 23, 2020
Date of Acceptance: Sep 21, 2020
Date of Publishing: Nov 01, 2020
AUTHOR DECLARATION:
• Financial or Other Competing Interests: None
• Was Ethics Committee Approval obtained for this study? Yes
• Was informed consent obtained from the subjects involved in the study? Yes
• For any images presented appropriate consent has been obtained from the subjects. NA
PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Jun 05, 2020
• Manual Googling: Sep 12, 2020
• iThenticate Software: Oct 26, 2020 (3%)
ETYMOLOGY: Author Origin
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