Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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On Sep 2018




Prof. Somashekhar Nimbalkar

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Prof. Somashekhar Nimbalkar
Head, Department of Pediatrics, Pramukhswami Medical College, Karamsad
Chairman, Research Group, Charutar Arogya Mandal, Karamsad
National Joint Coordinator - Advanced IAP NNF NRP Program
Ex-Member, Governing Body, National Neonatology Forum, New Delhi
Ex-President - National Neonatology Forum Gujarat State Chapter
Department of Pediatrics, Pramukhswami Medical College, Karamsad, Anand, Gujarat.
On Sep 2018




Dr. Kalyani R

"Journal of Clinical and Diagnostic Research is at present a well-known Indian originated scientific journal which started with a humble beginning. I have been associated with this journal since many years. I appreciate the Editor, Dr. Hemant Jain, for his constant effort in bringing up this journal to the present status right from the scratch. The journal is multidisciplinary. It encourages in publishing the scientific articles from postgraduates and also the beginners who start their career. At the same time the journal also caters for the high quality articles from specialty and super-specialty researchers. Hence it provides a platform for the scientist and researchers to publish. The other aspect of it is, the readers get the information regarding the most recent developments in science which can be used for teaching, research, treating patients and to some extent take preventive measures against certain diseases. The journal is contributing immensely to the society at national and international level."



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Professor and Head
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Sri Devaraj Urs Medical College
Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka
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Dr. Saumya Navit

"As a peer-reviewed journal, the Journal of Clinical and Diagnostic Research provides an opportunity to researchers, scientists and budding professionals to explore the developments in the field of medicine and dentistry and their varied specialities, thus extending our view on biological diversities of living species in relation to medicine.
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Dr Saumya Navit
Professor and Head
Department of Pediatric Dentistry
Saraswati Dental College
Lucknow
On Sep 2018




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"My sincere attachment with JCDR as an author as well as reviewer is a learning experience . Their systematic approach in publication of article in various categories is really praiseworthy.
Their prompt and timely response to review's query and the manner in which they have set the reviewing process helps in extracting the best possible scientific writings for publication.
It's a honour and pride to be a part of the JCDR team. My very best wishes to JCDR and hope it will sparkle up above the sky as a high indexed journal in near future."



Dr. Arunava Biswas
MD, DM (Clinical Pharmacology)
Assistant Professor
Department of Pharmacology
Calcutta National Medical College & Hospital , Kolkata




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Best regards,
C.S. Ramesh Babu,
Associate Professor of Anatomy,
Muzaffarnagar Medical College,
Muzaffarnagar.
On Aug 2018




Dr. Arundhathi. S
"Journal of Clinical and Diagnostic Research (JCDR) is a reputed peer reviewed journal and is constantly involved in publishing high quality research articles related to medicine. Its been a great pleasure to be associated with this esteemed journal as a reviewer and as an author for a couple of years. The editorial board consists of many dedicated and reputed experts as its members and they are doing an appreciable work in guiding budding researchers. JCDR is doing a commendable job in scientific research by promoting excellent quality research & review articles and case reports & series. The reviewers provide appropriate suggestions that improve the quality of articles. I strongly recommend my fraternity to encourage JCDR by contributing their valuable research work in this widely accepted, user friendly journal. I hope my collaboration with JCDR will continue for a long time".



Dr. Arundhathi. S
MBBS, MD (Pathology),
Sanjay Gandhi institute of trauma and orthopedics,
Bengaluru.
On Aug 2018




Dr. Mamta Gupta,
"It gives me great pleasure to be associated with JCDR, since last 2-3 years. Since then I have authored, co-authored and reviewed about 25 articles in JCDR. I thank JCDR for giving me an opportunity to improve my own skills as an author and a reviewer.
It 's a multispecialty journal, publishing high quality articles. It gives a platform to the authors to publish their research work which can be available for everyone across the globe to read. The best thing about JCDR is that the full articles of all medical specialties are available as pdf/html for reading free of cost or without institutional subscription, which is not there for other journals. For those who have problem in writing manuscript or do statistical work, JCDR comes for their rescue.
The journal has a monthly publication and the articles are published quite fast. In time compared to other journals. The on-line first publication is also a great advantage and facility to review one's own articles before going to print. The response to any query and permission if required, is quite fast; this is quite commendable. I have a very good experience about seeking quick permission for quoting a photograph (Fig.) from a JCDR article for my chapter authored in an E book. I never thought it would be so easy. No hassles.
Reviewing articles is no less a pain staking process and requires in depth perception, knowledge about the topic for review. It requires time and concentration, yet I enjoy doing it. The JCDR website especially for the reviewers is quite user friendly. My suggestions for improving the journal is, more strict review process, so that only high quality articles are published. I find a a good number of articles in Obst. Gynae, hence, a new journal for this specialty titled JCDR-OG can be started. May be a bimonthly or quarterly publication to begin with. Only selected articles should find a place in it.
An yearly reward for the best article authored can also incentivize the authors. Though the process of finding the best article will be not be very easy. I do not know how reviewing process can be improved. If an article is being reviewed by two reviewers, then opinion of one can be communicated to the other or the final opinion of the editor can be communicated to the reviewer if requested for. This will help one’s reviewing skills.
My best wishes to Dr. Hemant Jain and all the editorial staff of JCDR for their untiring efforts to bring out this journal. I strongly recommend medical fraternity to publish their valuable research work in this esteemed journal, JCDR".



Dr. Mamta Gupta
Consultant
(Ex HOD Obs &Gynae, Hindu Rao Hospital and associated NDMC Medical College, Delhi)
Aug 2018




Dr. Rajendra Kumar Ghritlaharey

"I wish to thank Dr. Hemant Jain, Editor-in-Chief Journal of Clinical and Diagnostic Research (JCDR), for asking me to write up few words.
Writing is the representation of language in a textual medium i e; into the words and sentences on paper. Quality medical manuscript writing in particular, demands not only a high-quality research, but also requires accurate and concise communication of findings and conclusions, with adherence to particular journal guidelines. In medical field whether working in teaching, private, or in corporate institution, everyone wants to excel in his / her own field and get recognised by making manuscripts publication.


Authors are the souls of any journal, and deserve much respect. To publish a journal manuscripts are needed from authors. Authors have a great responsibility for producing facts of their work in terms of number and results truthfully and an individual honesty is expected from authors in this regards. Both ways its true "No authors-No manuscripts-No journals" and "No journals–No manuscripts–No authors". Reviewing a manuscript is also a very responsible and important task of any peer-reviewed journal and to be taken seriously. It needs knowledge on the subject, sincerity, honesty and determination. Although the process of reviewing a manuscript is a time consuming task butit is expected to give one's best remarks within the time frame of the journal.
Salient features of the JCDR: It is a biomedical, multidisciplinary (including all medical and dental specialities), e-journal, with wide scope and extensive author support. At the same time, a free text of manuscript is available in HTML and PDF format. There is fast growing authorship and readership with JCDR as this can be judged by the number of articles published in it i e; in Feb 2007 of its first issue, it contained 5 articles only, and now in its recent volume published in April 2011, it contained 67 manuscripts. This e-journal is fulfilling the commitments and objectives sincerely, (as stated by Editor-in-chief in his preface to first edition) i e; to encourage physicians through the internet, especially from the developing countries who witness a spectrum of disease and acquire a wealth of knowledge to publish their experiences to benefit the medical community in patients care. I also feel that many of us have work of substance, newer ideas, adequate clinical materials but poor in medical writing and hesitation to submit the work and need help. JCDR provides authors help in this regards.
Timely publication of journal: Publication of manuscripts and bringing out the issue in time is one of the positive aspects of JCDR and is possible with strong support team in terms of peer reviewers, proof reading, language check, computer operators, etc. This is one of the great reasons for authors to submit their work with JCDR. Another best part of JCDR is "Online first Publications" facilities available for the authors. This facility not only provides the prompt publications of the manuscripts but at the same time also early availability of the manuscripts for the readers.
Indexation and online availability: Indexation transforms the journal in some sense from its local ownership to the worldwide professional community and to the public.JCDR is indexed with Embase & EMbiology, Google Scholar, Index Copernicus, Chemical Abstracts Service, Journal seek Database, Indian Science Abstracts, to name few of them. Manuscriptspublished in JCDR are available on major search engines ie; google, yahoo, msn.
In the era of fast growing newer technologies, and in computer and internet friendly environment the manuscripts preparation, submission, review, revision, etc and all can be done and checked with a click from all corer of the world, at any time. Of course there is always a scope for improvement in every field and none is perfect. To progress, one needs to identify the areas of one's weakness and to strengthen them.
It is well said that "happy beginning is half done" and it fits perfectly with JCDR. It has grown considerably and I feel it has already grown up from its infancy to adolescence, achieving the status of standard online e-journal form Indian continent since its inception in Feb 2007. This had been made possible due to the efforts and the hard work put in it. The way the JCDR is improving with every new volume, with good quality original manuscripts, makes it a quality journal for readers. I must thank and congratulate Dr Hemant Jain, Editor-in-Chief JCDR and his team for their sincere efforts, dedication, and determination for making JCDR a fast growing journal.
Every one of us: authors, reviewers, editors, and publisher are responsible for enhancing the stature of the journal. I wish for a great success for JCDR."



Thanking you
With sincere regards
Dr. Rajendra Kumar Ghritlaharey, M.S., M. Ch., FAIS
Associate Professor,
Department of Paediatric Surgery, Gandhi Medical College & Associated
Kamla Nehru & Hamidia Hospitals Bhopal, Madhya Pradesh 462 001 (India)
E-mail: drrajendrak1@rediffmail.com
On May 11,2011




Dr. Shankar P.R.

"On looking back through my Gmail archives after being requested by the journal to write a short editorial about my experiences of publishing with the Journal of Clinical and Diagnostic Research (JCDR), I came across an e-mail from Dr. Hemant Jain, Editor, in March 2007, which introduced the new electronic journal. The main features of the journal which were outlined in the e-mail were extensive author support, cash rewards, the peer review process, and other salient features of the journal.
Over a span of over four years, we (I and my colleagues) have published around 25 articles in the journal. In this editorial, I plan to briefly discuss my experiences of publishing with JCDR and the strengths of the journal and to finally address the areas for improvement.
My experiences of publishing with JCDR: Overall, my experiences of publishing withJCDR have been positive. The best point about the journal is that it responds to queries from the author. This may seem to be simple and not too much to ask for, but unfortunately, many journals in the subcontinent and from many developing countries do not respond or they respond with a long delay to the queries from the authors 1. The reasons could be many, including lack of optimal secretarial and other support. Another problem with many journals is the slowness of the review process. Editorial processing and peer review can take anywhere between a year to two years with some journals. Also, some journals do not keep the contributors informed about the progress of the review process. Due to the long review process, the articles can lose their relevance and topicality. A major benefit with JCDR is the timeliness and promptness of its response. In Dr Jain's e-mail which was sent to me in 2007, before the introduction of the Pre-publishing system, he had stated that he had received my submission and that he would get back to me within seven days and he did!
Most of the manuscripts are published within 3 to 4 months of their submission if they are found to be suitable after the review process. JCDR is published bimonthly and the accepted articles were usually published in the next issue. Recently, due to the increased volume of the submissions, the review process has become slower and it ?? Section can take from 4 to 6 months for the articles to be reviewed. The journal has an extensive author support system and it has recently introduced a paid expedited review process. The journal also mentions the average time for processing the manuscript under different submission systems - regular submission and expedited review.
Strengths of the journal: The journal has an online first facility in which the accepted manuscripts may be published on the website before being included in a regular issue of the journal. This cuts down the time between their acceptance and the publication. The journal is indexed in many databases, though not in PubMed. The editorial board should now take steps to index the journal in PubMed. The journal has a system of notifying readers through e-mail when a new issue is released. Also, the articles are available in both the HTML and the PDF formats. I especially like the new and colorful page format of the journal. Also, the access statistics of the articles are available. The prepublication and the manuscript tracking system are also helpful for the authors.
Areas for improvement: In certain cases, I felt that the peer review process of the manuscripts was not up to international standards and that it should be strengthened. Also, the number of manuscripts in an issue is high and it may be difficult for readers to go through all of them. The journal can consider tightening of the peer review process and increasing the quality standards for the acceptance of the manuscripts. I faced occasional problems with the online manuscript submission (Pre-publishing) system, which have to be addressed.
Overall, the publishing process with JCDR has been smooth, quick and relatively hassle free and I can recommend other authors to consider the journal as an outlet for their work."



Dr. P. Ravi Shankar
KIST Medical College, P.O. Box 14142, Kathmandu, Nepal.
E-mail: ravi.dr.shankar@gmail.com
On April 2011
Anuradha

Dear team JCDR, I would like to thank you for the very professional and polite service provided by everyone at JCDR. While i have been in the field of writing and editing for sometime, this has been my first attempt in publishing a scientific paper.Thank you for hand-holding me through the process.


Dr. Anuradha
E-mail: anuradha2nittur@gmail.com
On Jan 2020

Important Notice

Reviews
Year : 2026 | Month : September | Volume : 20 | Issue : 9 | Page : YE01 - YE04 Full Version

ACL Reconstruction with Enhanced Physiotherapy Interventions and Early Rehabilitation: A Narrative Review


Published: September 1, 2026 | DOI: https://doi.org/10.7860/JCDR/2026/87296.24325
Faiyazuddeen Kuthbudeen, Muthukumaran Jothilingam

1. Research Scholar, School of Physiotherapy, Sri Balaji Vidyapeeth Deemed to be University, Chennai Campus, Tamil Nadu, India. 2. Professor, School of Physiotherapy, Sri Balaji Vidyapeeth Deemed to be University, Chennai Campus, Tamil Nadu, India.

Correspondence Address :
Mr. Faiyazuddeen Kuthbudeen,
Research Scholar, School of Physiotherapy, Sri Balaji Vidyapeeth Deemed to be University, Chennai Campus-603110, Tamil Nadu, India.
E-mail: fiaz16@rediffmail.com

Abstract

Anterior Cruciate Ligament Reconstruction (ACLR) is a common surgical knee procedure that requires intensive postoperative rehabilitation by the patient. Although ACLR restores the knee’s mechanical stability, patients often experience postoperative limitations. This study aimed to examine the supplementary physiotherapy interventions incorporated into standard rehabilitation programs that enhance early-stage ACLR rehabilitation. In October 2025, a literature review was performed utilising electronic databases. The primary outcomes assessed included pain, oedema, muscle strength, Range Of Motion (ROM), and knee function. For this review, 10 studies were selected that fulfilled the inclusion criteria (total n=210). The studies analysed the efficacy of Kinesio Taping (KT), Whole-Body Vibration (WBV), local vibration training, Trigger Point Dry Needling (TrP-DN), high tone power therapy, alternating magnetic field, and an App-based active muscle training program. The majority of the additional physiotherapy interventions demonstrated improvements in pain, oedema, ROM, knee muscle strength, or knee function during the early stages of postoperative ACL rehabilitation. With the exception of one study, no adverse events were reported in the included studies, indicating the safety of the physiotherapy interventions discussed. Further comprehensive research is warranted in this domain.

Keywords

Anterior cruciate ligament reconstruction, Postoperative, Knee therapy

ACL injuries are among the most common and debilitating sports-related injuries, often leading to long-term functional impairments if not properly treated. The ACL is essential for the kinematics of the knee joint, as it restricts the anterior movement of the tibia and stabilises the knee joint (1). It also contains mechanoreceptors that play a critical role in maintaining neuromuscular control of the joint. At the same time, it is a structure that, when injured, is one of the most common and serious locomotor injuries (2). The result of an ACL rupture is a disturbance in the biomechanics of the joint, which can lead to the development of abnormal movement patterns and chronic instability, resulting in functional loss during dynamic tasks and potentially causing secondary damage to the menisci and cartilage (3),(4). A complete ACL rupture typically indicates the need for surgical reconstruction. It is important to highlight that the prognosis for patients following surgery is heavily dependent on the rehabilitation that is implemented (5).

Although ACLR restores mechanical stability of the knee, many patients continue to experience postoperative pain (6), joint effusion (7), muscle weakness (8), and restricted ROM for prolonged periods, which may result in functional impairment and diminished quality of life (9). Conventional physiotherapy alone often does not adequately address these sequelae, underscoring the need to optimise and intensify existing rehabilitation protocols (10), particularly during the early postoperative period. Numerous systematic reviews have evaluated the impact of physiotherapeutic interventions following ACLR, encompassing studies of early and late postoperative rehabilitation (11),(12),(13), preoperative “prehabilitation” programs, and combined pre and postoperative approaches (14),(15). In contrast, the present study focuses exclusively on interventions implemented in the early phase of postoperative ACL rehabilitation.

This review specifically analysed the early phase of ACL rehabilitation, as this stage may be constrained by postoperative complications such as pain or swelling, which frequently challenge both clinicians and patients during the first weeks postsurgery (16). The occurrence of swelling results in diminished quadriceps strength due to arthrogenic muscle inhibition (17), and pain complicates both exercise and functional performance (18). This review sought to explore which physiotherapy approaches effectively alleviate pain, minimise swelling, enhance knee mobility, strengthen muscles, and improve functional recovery during the early phase following ACLR. Accordingly, the study aimed to evaluate additional physiotherapy modalities integrated into conventional rehabilitation programs to optimise early postoperative outcomes after ACLR.


Effect of Kinesio Taping (KT) on ACLR

The KT functions by microscopically elevating the skin to relieve pressure in the interstitial space, thereby decreasing the pressure on subcutaneous nociceptors and mitigating pain according to the gate control theory (19). This mechanical elevation concurrently improves localised blood flow, hastens lymphatic drainage, and offers ongoing somatosensory feedback to enhance joint proprioception (20). In clinical practice, it acts as a beneficial adjunct therapy for immediate, short-term pain alleviation, reduction of oedema, and facilitation of functional movement without limiting the ROM (21),(22). Nevertheless, significant limitations remain; literature reviews indicate a deficiency of high-quality, long-term evidence, with therapeutic outcomes frequently not surpassing those of sham taping.

Three studies explored the effects of KT during the early postoperative phase after ACLR. Labianca L et al., (2022) enrolled 52 men (ages 18-45 years) after gracilis and semitendinosus autograft, assigning them on postoperative day two to KT every five days for four weeks plus standard rehab or rehab alone. At two and four weeks, KT significantly reduced pain and oedema (p-value <0.05), but did not improve ROM or knee function (p-value >0.05) (23).

Balki S et al., (2016) studied 30 men (ages 18-39 years) post-ACLR (hamstring tendon autograft and tibialis posterior or peroneus longus allograft), assigning them to either muscle/lymphatic KT or placebo KT, along with a standardised 12-week rehab program. Measurements on postoperative day four, after five and 10 days of KT, and at one and three months, showed KT significantly improved knee swelling, pain, hamstring strength, and flexion ROM (p-value <0.05), but not subjective function, extension, or extensor strength (p-value >0.05) (24).

Laborie M et al., (2015) assessed KT’s role in reducing early postoperative pain in 57 patients (44 men, 13 women) after hamstring tendon graft, with KT applied for three days alongside anaesthesia-analgesia or anaesthesia-analgesia alone. Pain was measured at baseline and for three days after taping; KT did not significantly reduce early pain compared to control (p-value >0.05). Overall, KT may help reduce pain and swelling after ACLR, though evidence for improvements in function and ROM is inconsistent (25).

The influence of vibration training during the early stages of rehabilitation post-ACLR vibration training is generally administered through WBV platforms. The swift mechanical oscillations induce ongoing micro-instability, activating muscle spindle stretch reflexes that compel the neuromuscular system to refine motor unit recruitment and synchronisation (26). From a mechanical perspective, this rhythmic loading promotes osteoblast activity, thereby improving bone mineral density, while also elevating localised nitric oxide production to enhance blood circulation (27). Clinically, it functions as a remarkably effective low-impact intervention for groups who are unable to engage in conventional high-impact resistance training.

Two studies evaluating WBV and one assessing Local Vibration Therapy (LVT) during early rehabilitation after ACLR were analysed. Berschin G et al., randomised 40 patients (29 men, 11 women; aged 25-39) post-patellar tendon graft to eight weeks of WBV or standard rehab, with assessments at baseline, weeks 5, 8, and 11; WBV showed no significant gains in ROM, strength, or knee function versus control (p-value >0.05) (28).

Pistone EM et al., (2016) evaluated 34 patients one month after ACLR with hamstring tendon autograft, randomly allocating them to either four weeks of WBV training plus standard rehabilitation or to standard rehabilitation alone. Strength and balance were measured at baseline, and again at two and three months postsurgery. The WBV group demonstrated significant improvements in knee flexor strength symmetry and knee function (p-value <0.05) compared to control, but there was no significant difference in knee extensor strength symmetry between groups (p-value >0.05) (29).

Coulondre C et al., (2022) investigated the effect of LVT on quadriceps strength in 23 subjects (13 males, 10 females, aged 18-50 years) after ACLR with hamstring or patellar tendon autografts. Participants were allocated to receive either 24 LVT or 24 standard rehab sessions over 10 weeks, or 24 standard rehab sessions alone. Measurements taken before and after the intervention revealed that the LVT group had significantly greater improvements in extensor muscle strength compared to controls (p-value <0.05), but there were no significant differences in limb symmetry or functional test outcomes (p-value >0.05) (30).

Impact of Various Interventions on the Initial Rehabilitation following ACLR

Four investigations focused on a range of alternative physiotherapy treatments. Trigger Point Dry Needling (TrP-DN) is an invasive intramuscular procedure aimed at hyperirritable, taut bands of skeletal muscle fibres. Its fundamental mechanism involves the insertion of a slender monofilament needle into dysfunctional motor endplates, which mechanically disrupts shortened sarcomeres and induces a Local Twitch Response (LTR). This swift contraction aids in restoring the resting length of sarcomeres, eliminates accumulated chemical nociceptors, and activates spinal A-delta fibres to initiate descending inhibitory pathways that mitigate central sensitisation (31). TrP-DN is recognised as an effective technique for the immediate, short-term alleviation of localised or referred myofascial pain, while also quickly restoring joint ROM (32). It is commonly utilised by clinicians to address myofascial pain syndrome, tension headaches, and chronic athletic strains. Nevertheless, significant limitations remain due to a notable absence of high-quality evidence proving long-term advantages over non-invasive treatments.

Additionally, potential risks encompass post-treatment soreness, localised bruising, compromised immunity, and active skin lesions (33). TrPDN was evaluated by Velásquez-Saornil J et al., in 44 participants (28 males, 16 females; aged 19-51 years) after ACLR with patellar or hamstring tendon grafts. Subjects were randomised within 12-19 days postoperative to a single vastus medialis TrPDN intervention plus 5-week rehabilitation, or rehabilitation alone. Outcomes were measured at baseline, immediately, and one day, one week, and five weeks postintervention. TrPDN increased pain immediately postintervention (p-value <0.05), but also improved ROM and knee function (p-value <0.05), with no reported changes in stability (34).

High-Tone Power Therapy (HiToP) employs high-energy, medium-frequency alternating electrical currents (ranging from 4,096 to 32,768 Hz) that are delivered directly into intracellular structures. The primary mechanism of action is based on the simultaneous modulation of frequency and amplitude, which generates a cellular resonance effect that facilitates metabolic normalisation, eliminates waste, and disperses inflammatory mediators, while also diminishing neuromuscular hypertonia. In clinical practice, HiToP is utilised as a sophisticated adjunctive treatment for neuro-musculoskeletal pain. It is extensively used to decrease spasticity and enhance gait speed in post-stroke rehabilitation, relieve chronic diabetic or radicular neuropathic pain (35). Nevertheless, significant limitations remain due to the absence of comprehensive, large-scale clinical trials, which complicates the ability to determine its specific efficacy apart from other concurrent therapies. Ogrodzka-Ciechanowicz K et al., investigated quadriceps electrostimulation combined with HiToP therapy versus standard rehabilitation in 35 male ACLR patients (ages 21-50 years, hamstring tendon graft) recruited on postoperative day 11. The HiToP group received one hour of quadriceps-targeted HiToP per rehab session over six months, while controls had standard rehab. At six months, the HiToP group showed significant improvements in extensor strength, knee and thigh circumference, knee extension, and knee function (p-value <0.05), but pain levels did not differ significantly between groups (p-value >0.05) (36). In their second study, Ogrodzka-Ciechanowicz K et al., studied 38 patients (28 males, 10 females; ages 18-40 years) on the first postoperative day after ACLR with a semitendinosus tendon autograft, randomly assigning them to either 10 days of 30-minute alternating magnetic field therapy or a placebo protocol. Daily measurements for 11 days revealed that alternating magnetic field therapy did not significantly improve knee joint effusion or active ROM compared to placebo (p-value >0.05) (37).

App-based active muscle training provides digital exercise programs through algorithms, prerecorded media, or Artificial Intelligence (AI) computer vision. Its main function promotes neuromuscular adaptations- such as muscle protein synthesis and enhanced motor unit recruitment- by utilising progressive overload and repetitive practice. Simultaneously, it incorporates behavioural architecture elements like push notifications, real-time audio-visual feedback, and gamification to systematically enhance exercise adherence. Clinically, it acts as a highly scalable, remote digital intervention that enhances physical function, boosts muscular strength, and alleviates pain in patients dealing with knee osteoarthritis, post-stroke spasticity, geriatric sarcopenia, or orthopaedic postoperative recovery (38),(39). Nevertheless, significant drawbacks include high user dropout rates and a total lack of hands-on medical supervision, which increases the risk of improper movement mechanics and injury. Clausen JD et al., studied 26 individuals (12 men, 14 women) immediately after ACLR with hamstring graft, randomising them to three weeks of app-based active muscle training (serious gaming, five times daily) or standard rehabilitation only. At six weeks postoperative, the app-based training group showed significantly greater improvements in maximum strength (p-value<0.05), with no significant changes in knee function or pain versus the control group (p-value >0.05) (40).

Risk of Bias of the Included Studies

Across the nine randomised trials and one non-randomised trial, the risk of bias from the randomisation process and selective reporting was consistently judged as low, suggesting that sequence generation, allocation concealment, and outcome reporting were generally appropriate. The most frequent concerns arose in the domains of deviations from the intended interventions and measurement of outcomes, where several studies were rated as having “some concerns,” indicating possible issues with adherence to the assigned intervention, co-interventions, or lack of blinding of outcome assessors. One study (Coulondre C et al., 2022) showed high-risk of bias due to substantial missing outcome data, leading to a high overall risk rating (30), while two studies (Velázquez-Saornil J et al., 2017; Ogrodzka Ciechanowicz K et al., II, 2021) were at overall low risk (34),(36). Collectively, the evidence base is reasonably robust but may over or underestimate true intervention effects due to performance and detection biases, and results should be interpreted with appropriate caution.

Discussion

This narrative review examined 10 studies on additional physiotherapy interventions during early rehabilitation after ACLR, focusing on improvements in pain, swelling, ROM, muscle strength, and knee function. Three studies investigated KT: most showed significant reductions in pain and swelling, though functional and strength improvements were inconsistent. Notably, one study with only a 3-day KT application reported no pain relief (26), and only Balki S et al., showed significant gains in knee flexion ROM and flexor strength (24).

Three studies evaluated vibration training. Results were mixed; Berschin G et al., found no benefit in ROM, muscle strength, or function (28), whereas Pistone EM et al., reported improvements in knee flexor strength and function, possibly due to later intervention timing (29). LVT showed improvements in knee extension strength without significantly enhancing function (30).

Four other interventions were studied individually. TrPDN improved knee ROM and function but caused transient pain immediately after treatment (34). Dry needling during late-stage ACLR rehabilitation also reduced pain and improved flexion. HiToP therapy enhanced swelling, ROM, knee function, and extensor strength, though not pain (36). Alternating magnetic field therapy showed no significant effects on oedema or ROM, while app-based active muscle training improved knee extensor strength without impacting pain or swelling (37),(40).

The studies displayed considerable methodological heterogeneity, with varied designs, patient populations, intervention protocols, and outcome measures, limiting comparability and generalisation.

Overall, the reviewed physiotherapy interventions demonstrated potential benefits for early ACL rehabilitation, especially in managing pain, swelling, and muscle strength. However, inconsistencies and methodological limitations highlight the need for standardised protocols and larger, high-quality trials to confirm these findings and optimise rehabilitation strategies post-ACLR.

Conclusion

In this review, most of the additional physiotherapy interventions analysed have been found to improve pain, oedema, ROM, knee muscle strength, or knee function during the early postoperative rehabilitation phase following ACL surgery. Except for one study, no adverse events were reported in the included studies, which illustrate the safety of the physiotherapy interventions discussed. It is also noteworthy that in some studies, no significant differences were observed between the experimental and control groups. Further extensive research is essential to assess the physiotherapy interventions reviewed, taking into account standardised methodologies, a larger participant population, a longer study duration including follow-up, validated assessment techniques, and relevant outcome measures.

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DOI and Others

DOI: 10.7860/JCDR/2026/87296.24325

Date of Submission: Jan 09, 2026
Date of Peer Review: Apr 11, 2026
Date of Acceptance: Jun 02, 2026
Date of Publishing: Sep 01, 2026

Author declaration:
• Financial or Other Competing Interests: None
• Was informed consent obtained from the subjects involved in the study? NA
• For any images presented appropriate consent has been obtained from the subjects. NA

PLAGIARISM CHECKING METHODS:
• Plagiarism X-checker: Feb 10, 2026
• Manual Googling: May 27, 2026
• iThenticate Software: May 30, 2026 (1%)

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