Cerebral Venous Sinus Thrombosis Complicating Adult Onset Nephrotic SyndromeCorrespondence Address :
Dr. Arun Karat Anandan,
Senior Resident, Department of Nephrology, Government TD Medical College, Alappuzha-688001, Kerala, India.
Nephrotic syndrome is well known for its hypercoagulable state and thrombotic complications. This warrants cautious management of the disease with meticulous monitoring for thrombotic complications as it carries high morbidity and mortality than the original disease itself most often. Here, we present a case of adult onset nephrotic syndrome referred to our centre for further evaluation and management. On detailed work up, she turned out to be a case of minimal change disease. During her recovery period in the hospital she developed headache and diplopia. Sudden onset of neurological symptoms in the background of a thrombotic milieu prompted us to do further neurological evaluation which revealed extensive cerebral venous sinus thrombosis. She received anticoagulation without delay. Although the condition is associated with high mortality our patient showed very good response to anticoagulation and she was discharged in a stable condition.
Anticoagulation, Diplopia, Hypercoagulable state, Minimal change disease
Arun Karat Anandan, Pradeep Balachandran, Arpitha Chowksey, Gomathy Sankaranarayanan, Usha Samuel. CEREBRAL VENOUS SINUS THROMBOSIS COMPLICATING ADULT ONSET NEPHROTIC SYNDROME. Journal of Clinical and Diagnostic Research [serial online] 2018 June [cited: 2018 Sep 20 ]; 12:OD01-OD03. Available from
Date of Submission: Jan 30, 2018
Date of Peer Review: Mar 28, 2018
Date of Acceptance: Apr 12, 2018
Date of Publishing: Jun 01, 2018
Financial OR OTHER COMPETING INTERESTS: None.
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