Childhood Onset Nephrotic Syndrome-A Journey Through Two PregnanciesCorrespondence Address :
Dr. Shashikiran Umakanth,
Professor and Head, Department of Medicine, Dr. TMA Pai Hospital, Udupi Melaka Manipal Medical College,
Manipal Academy of Higher Education,
Manipal, Karnataka, India.
Nephrotic Syndrome (NS), a unique renal disease complex associated with heavy proteinuria (protein excretion >3.5 gm/day), hypoalbuminemia (<30 gm/L) and peripheral oedema. It is a rare entity in pregnancy, with an incidence of about 0.012-0.025%. There have been very few reports of pregnancy with co-existing NS. We hereby report a case of steroid sensitive childhood onset NS, due to minimal change disease and her course through two pregnancies. While she had a relapse of NS during her first pregnancy, she sailed through her second pregnancy without relapse. Women with NS can have a good maternal and perinatal outcome with multidisciplinary approach. Pregnancy does not always worsen the existing NS by causing a relapse or disease progression.
Hypertension, Pregnancy, Proteinuria, Renal disease, Steroids
Shashikala K Bhat, Shashikiran Umakanth, Krupa Shah, AP Ashwini, Ravindra Prabhu. CHILDHOOD ONSET NEPHROTIC SYNDROME-A JOURNEY THROUGH TWO PREGNANCIES. Journal of Clinical and Diagnostic Research [serial online] 2018 July [cited: 2018 Sep 25 ]; 12:QD08-QD09. Available from
Date of Submission: Feb 18, 2018
Date of Peer Review: Apr 23, 2018
Date of Acceptance: May 11, 2018
Date of Publishing: Jul 01, 2018
FINANCIAL OR OTHER COMPETING INTERESTS: NONE.
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