Assessment of Blood Loss in Abdominal Myomectomy by Intramyometrial Vasopressin Administration Versus Conventional Tourniquet ApplicationCorrespondence Address :
Dr. Mriganka Mouli Saha,
97 Rabindranagar, PO Dankuni, Dist Hooghly, West Bengal-712311, India.
Introduction: Myomectomy is an invasive surgical procedure. It can be associated with intraoperative and postoperative complications like excessive haemorrhage. There are various methods to control haemorrhage like pharmacological and as well as mechanical methods.
Aim: This study was taken to compare intraoperative blood loss following abdominal myomectomy after receiving intramyometrial vasopressin or tourniquet application and to estimate postoperative reduction in haemoglobin & haematocrit values. Materials and Methods: The study was a randomised single blinded parallel group study. Total 48 patients were included in this study according to inclusion and exclusion criteria. All patients were divided into two groups i.e. ‘T’ and ‘V’ group, 24 in each group. ‘T’ group received conventional tourniquet application and ‘V’ group received intramyometrial vasopressin administration. The analyses in this study were both sided and p<0.05 was considered significant statistically. The Software used were Statistica version 6 (Tulsa, Oklahoma: Stat Soft Inc., 2001) and Graph Pad Prism version 5 (San Diego, California: Graph Pad Software Inc., 2007).
Results: The blood loss in the tourniquet group was significantly higher (p=<0.001). Postoperative haemoglobin and haematocrit were lower in tourniquet group than vasopressin group. There was significant fall in haemoglobin and haematocrit in postoperative period in both group (p=<0.001) but it was more in tourniquet group. Total five patients (three in tourniquet group and two in vasopressin group) had received one unit whole blood transfusion.
Conclusion: Intramyometrial vasopressin injection during myomectomy operation more effectively decreases the blood loss, need for blood transfusion and it causes less reduction in haemoglobin and haematocrit. Thereby it seems to be an effective method without having any risk of ischemic damage to the uterus.
Benign tumor, Surgical haemorrhage, Uterine myomectomy
Mriganka Mouli Saha, Khushboo, Subhash Chandra Biswas, Hajekul Alam, Gouri Sankar Kamilya, Madhumita Mukhopadhyay, et al.. ASSESSMENT OF BLOOD LOSS IN ABDOMINAL MYOMECTOMY BY INTRAMYOMETRIAL VASOPRESSIN ADMINISTRATION VERSUS CONVENTIONAL TOURNIQUET APPLICATION. Journal of Clinical and Diagnostic Research [serial online] 2016 May [cited: 2018 Oct 16 ]; 10:QC10-QC13. Available from
Date of Submission: Oct 24, 2015
Date of Peer Review: Dec 23, 2015
Date of Acceptance: Feb 09, 2016
Date of Publishing: May 01, 2016
Financial OR OTHER COMPETING INTERESTS: None.
- Emerging Sources Citation Index (Web of Science, thomsonreuters)
- Index Copernicus ICV 2016: 132.37
- Academic Search Complete Database
- Directory of Open Access Journals (DOAJ)
- Embase & EMbiology
- Google Scholar
- HINARI Access to Research in Health Programme
- Indian Science Abstracts (ISA)
- Journal seek Database
- Popline (reproductive health literature)