Schimidt Syndrome: An Unusual Cause of HypercalcaemiaCorrespondence Address :
Dr. Nisha Jose,
Assistant Professor, Department of General Medicine, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Autoimmune polyglandular syndrome type 2 also known as Schmidt syndrome. It is a rare disorder involving a combination of Addison’s disease with autoimmune thyroid disease with or without type 1 diabetes mellitus. In this case report one such patient with this rare syndrome is described who presented with hyperpigmentation of knuckles, palms and soles with significant weight loss for 2 months. At presentation she also had severe hypercalcaemia. Severe hypercalcaemia is rare and hypercalcaemia at the initial presentation of Addison’s disease is also unusual. The mechanism of hypercalcaemia in addisons and management of this patient is discussed.
Autoimmune polyendocrinopathies, Hypercalcaemia, Hypocortiolism
Nisha Jose, George Prashanth Kurian. SCHIMIDT SYNDROME: AN UNUSUAL
CAUSE OF HYPERCALCAEMIA. Journal of Clinical and Diagnostic Research [serial online] 2016 May [cited: 2019 Jan 23 ]; 10:OD21-OD22. Available from
Date of Submission: Sep 12, 2015
Date of Peer Review: Nov 4, 2015
Date of Acceptance: Dec 11, 2015
Date of Publishing: May 01, 2016
Financial OR OTHER COMPETING INTERESTS: None.
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