An Audit of Bone Mineral Density and Associated Factors in Patients with Lumbar Spinal Stenosis RC01-RC07
Dr. Seyed Mokhtar Esmaeilnejad-Ganji,
Department of Orthopedics, Babol University of Medical Sciences, Ganjafrooz Street, Babol, Mazandaran, Iran.
Introduction: Osteoporosis is a major global health problem and is commonly observed with lumbar stenosis in older people. It is stated that osteoporosis may cause progressive spinal deformities and stenosis in elderly patients.
Aim: To audit prevalence of low bone mineral density and associated factors in patients with lumbar spinal stenosis.
Materials and Methods: Patients with symptomatic lumbar spinal stenosis were recruited in this cross-sectional study, who had been referred to Shahid Beheshti hospital in Babol, Northern Iran, between 2016 and 2017. Lumbar spinal stenosis was diagnosed based on clinical symptoms and a stenotic lesion in the lumbar spine confirmed by magnetic resonance imaging. Low bone mineral density was confirmed based on World Health Organisation and International Society for Clinical Densitometry criteria. Demographic and laboratory parameters of the patients were collected. The data were analysed using SPSS by descriptive, ANOVA, logistic regression and Pearson correlation tests.
Results: Overall, 146 patients with lumbar stenosis were enrolled. Based on bone densitometry of spine and femur, 35 (24%) and 36 (24.7%) of the patients had osteoporosis. According to femoral densitometry, age (OR=1.311, 95% CI: 1.167-1.473), being a female (OR=3.391, 95% CI: 1.391-8.420) and being a homemaker (OR=3.675, 95% CI: 1.476-9.146) were found as risk factors for osteoporosis. Based on spinal densitometry, age (OR=1.283, 95% CI: 1.154-1.427) and being a female (OR=2.786, 95% CI: 1.106-7.019) were associated with osteoporosis. Significant correlations were observed between bone mineral density and red blood cell counts (r=+0.168, p=0.043) and vitamin D (r=+0.303, p<0.001).
Conclusion: The prevalence of low bone mineral density was considerable in the patients with lumbar spinal stenosis. Control of modifiable associated factors by physicians and healthcare administrators should lead to a better outcome of the disease in these patients.