Panhypopituitarism without Thrombosis due to Primary Antiphospholipid Syndrome OD10-OD11
Dr. Subodh Kumar Mahto,
Senior Resident, Department of Medicine, OPD Block, PGIMER, Dr. RML Hospital, New Delhi-110001, India.
Hypopituitarism is a clinical syndrome in which pituitary hormones deficiency is seen in many conditions. Antiphospholipid Syndrome (APS) is an autoimmune disease characterised by antiphospholipid antibodies, commonly manifests as venous or arterial thrombosis with recurrent foetal loss. We here by report a case of 40-year-old female who presented with bilateral swelling of lower limbs with exertional breathlessness along with feeling of cold extremities, easy fatigability, lethargy and decreased appetite for six months which turned out to be hypopituitarism with APS. Hormone replacement was started and she experienced a good clinical improvement.