Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

Users Online : 24203

Original article / research
Year : 2018 | Month : June | Volume : 12 | Issue : 6 | Page : UC05 - UC09

Comparing the Anaesthetic and Analgesic Efficacy of Caudal Levobupivacaine and Ropivacaine in Paediatric Patients

Sai Tejashree Veeravalli, B V Sunil, T V Shenoy

1. Senior Resident, Department of Anesthesia, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, Karnataka, India. 2. Associate Professor, Department of Anesthesia, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, Karnataka, India. 3. Professor, Department of Anesthesia, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, Karnataka, India.

Correspondence Address :
Dr. B V Sunil,
Associate Professor, Department of Anesthesia, Kasturba Medical College, Manipal Academy of Higher Education,
Mangalore, Karnataka, India.
E-mail: drsunilbv@gmail.com

Abstract

Introduction: Introduction of S enantiomer of bupivacaine is a major breakthrough in the history of local anaesthesia as the pharmacodynamics of these drugs were favourable in reducing the occurrence of cardiotoxicity, neurotoxicity and unintended motor blockade

Aim: To compare efficacy, postoperative analgesia and postoperative motor blockade of 0.25% levobupivacaine with 0.25% ropivacaine in caudal block for children, scheduled for lower abdominal and lowerlimb surgeries.

Materials and Methods: 80 children, ASA III, 1-10 years, weighing between 5-30 kg, scheduled for elective lower abdominal and lower limb surgeries were given single caudal injection of 1 mL/kg of either levobupivacaine or ropivacaine. Caudal block was given after general anaesthesia using sevoflurane as induction agent airway secured with laryngeal mask. Postoperative pain score was assessed using Children and Infants Postoperative Pain Scale (CHIPPS) scale in children less than 6 years and numerical scale for children more than 6 years. Motor recovery was assessed by modified Bromage scale.

Results: Onset of analgesia, duration of analgesia, postoperative pain and motor blockade were comparable between the two groups, of 40 each. Analgesia time was within 5 minutes in both the groups. Duration of analgesia was 404.867.6 minutes for levobupivacaine and 413.544.4 minutes for ropivacaine, which was not significant statistically. Postoperative analgesia was same between the two groups. It took 120 minutes for complete postoperative motor recovery. The motor recovery between the two groups was statistically not significant at immediate postoperative period (p=0.111), at 60 minutes (p=0.692).

Conclusion: We conclude that both 1 mL of 0.25% levobupivacaine and 0.25% ropivacaine provide similar effect caudal anaesthesia and analgesia with motor blockade for 120 minutes.

Keywords

Caudal block, Postoperative pain, Ropivacaine

How to cite this article :

Sai Tejashree Veeravalli, B V Sunil, T V Shenoy. COMPARING THE ANAESTHETIC AND ANALGESIC EFFICACY OF CAUDAL LEVOBUPIVACAINE AND ROPIVACAINE IN PAEDIATRIC PATIENTS. Journal of Clinical and Diagnostic Research [serial online] 2018 June [cited: 2018 Jun 23 ]; 12:UC05-UC09. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=June&volume=12&issue=6&page=UC05-UC09&id=11652

DOI and Others

DOI: 10.7860/JCDR/2018/34700.11652

Date of Submission: Nov 09, 2017
Date of Peer Review: Jan 19, 2018
Date of Acceptance: Apr 10, 2018
Date of Publishing: Jun 01, 2018

FINANCIAL OR OTHER COMPETING INTERESTS: None.

JCDR is now Monthly and more widely Indexed .
  • Emerging Sources Citation Index (Web of Science, thomsonreuters)
  • Index Copernicus ICV 2016: 132.37
  • SCOPUS
  • Academic Search Complete Database
  • Directory of Open Access Journals (DOAJ)
  • EBSCOhost
  • Embase & EMbiology
  • Google Scholar
  • HINARI Access to Research in Health Programme
  • Indian Science Abstracts (ISA)
  • Journal seek Database
  • Google
  • Popline (reproductive health literature)
  • www.omnimedicalsearch.com