Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2018 | Month : June | Volume : 12 | Issue : 6 | Page : SC05 - SC08

Comparative Study of 3% Hypertonic Saline Nebulisation Versus 0.9% Normal Saline Nebulisation for Treating Acute Bronchiolitis

Tanveer Bashir, Kallem Venkat Reddy, Kaiser Ahmed, Saima Shafi

1. Senior Resident, Department of Neonatology, Fernandez Hospital, Hyderabad, Telangana, India. 2. Senior Resident, Department of Neonatology, Fernandez Hospital, Hyderabad, Telangana, India. 3. Head and Professor, Department of Paediatrics, Government Medical College, Srinagar, Jammu and Kashmir, India. 4. Assistant Professor, Department of Computer Science, Sri Sukhmani Institute of Engineering and Technology, Chandigrah, Punjab, India.

Correspondence Address :
Dr. Tanveer Bashir,
Senior Resident, Fernandez Hospital, Hyderguda-500048, Hyderabad, Telangana, India.
E-mail: drtanveer.151@gmail.com

Abstract

Introduction: Bronchiolitis is commonly noticed condition in children, especially in infants and characterised by inflammation of bronchioles. Inspite of this common occurrence the evidence for the treatment options is limited.

Aim: To compare the effect of 3% Hypertonic Saline (HS) nebulisation with 0.9% Normal Saline (NS) nebulisation for treating acute bronchiolitis in moderately ill hospitalised infants and children (<18 months) on Length Of Hospital Stay (LOS) and improvement in clinical severity score.

Materials and Methods: This is a randomised controlled trial, done in a tertiary care paediatric hospital over a period of one year from April 2014 to March 2015. Out of 189 children randomised, 96 patients and 93 patients received HS nebulisation and NS nebulisation respectively. Treating doctors and patients were blinded to intervention and outcome.

Results: Reduction in clinical severity score in 3% HS nebulisation group was 2.26 (0.684) and in 0.9% NS nebulisation group was 1.23 (0.492), with statistically significant p<0.001. LOS in 3% HS nebulisation group was 1.45 (0.540) days and in 0.9% NS nebulisation group was 2.35 (0.619) days with mean difference of 0.91 (0.084) day with statistically significant p<0.001.

Conclusion: This study demonstrates that 3% HS nebulisation is safe and effective treatment for infants up to the age of 18 months hospitalised with acute bronchiolitis and decreases hospital stay by about one day.

Keywords

Bronchiolitis, Nebulisation, Respiratory tract infection

How to cite this article :

Tanveer Bashir, Kallem Venkat Reddy, Kaiser Ahmed, Saima Shafi. COMPARATIVE STUDY OF 3% HYPERTONIC SALINE NEBULISATION VERSUS 0.9% NORMAL SALINE NEBULISATION FOR TREATING ACUTE BRONCHIOLITIS. Journal of Clinical and Diagnostic Research [serial online] 2018 June [cited: 2018 Jun 23 ]; 12:SC05-SC08. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=June&volume=12&issue=6&page=SC05-SC08&id=11594

DOI and Others

DOI: 10.7860/JCDR/2018/34766.11594

Date of Submission: Nov 14, 2017
Date of Peer Review: Feb 07, 2018
Date of Acceptance: Mar 19, 2018
Date of Publishing: Jun 01, 2018

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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