Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2018 | Month : June | Volume : 12 | Issue : 6 | Page : BC05 - BC08

Serum Erythropoietin Level in Type II Diabetic Nephropathy

Zainab Abbas Jwad, Haider Kamel Zaidan, Mahmoud Hussein Hadwan

1. Researcher, Department of Chemistry, University of Babylon, Hilla, Babylon, Iraq. 2. Professor, Department of Biology, University of Babylon, Hilla, Babylon, Iraq. 3. Assistant Professor, Department of Chemistry, University of Babylon, Hilla, Babylon, Iraq.

Correspondence Address :
Dr. Mahmoud Hussein Hadwan,
Al-Imam Ali St. hilla, Hilla, Babylon, Iraq.
E-mail: mahmoudhadwan@gmail.com

Abstract

Introduction: Diabetes is a disease characterised by poor glycaemic control and development of various complications with age. Diabetic complications include development of nephropathy as well as other complications.

Aim: The study was aimed to elucidate the consequences of diabetic nephropathy on erythropoietin levels and microalbuminuria.

Materials and Methods: A total of 66 subjects with Type II Diabetes Mellitus (T2DM) with and without microalbuminuria and 22 healthy subjects were enrolled in the present study. The following case-control study was completed in Al-Najaf Centre for Diabetes and Endocrinology, Al-Najaf City, Iraq from March 2016 to May 2016. Serum erythropoietin levels and microalbuminuria concentrations were documented in addition to demographic and biochemical data.

Results: Serum erythropoietin concentrations were decreased significantly in patients with T2DM compared to that of healthy control subjects. Microalbuminuria concentrations were increased significantly in patients with T2DM compared to that of healthy control subjects.

Conclusion: Microalbuminuria and erythropoietin levels can be used to assess the occurance of complications in patients with diabetic nephropathy.

Keywords

Chronic kidney disease, End-stage renal disease, Haemoglobin, Hyperglycaemia, Renal function

How to cite this article :

Zainab Abbas Jwad, Haider Kamel Zaidan, Mahmoud Hussein Hadwan. SERUM ERYTHROPOIETIN LEVEL IN TYPE II DIABETIC NEPHROPATHY. Journal of Clinical and Diagnostic Research [serial online] 2018 June [cited: 2018 Jun 24 ]; 12:BC05-BC08. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=June&volume=12&issue=6&page=BC05-BC08&id=11631

DOI and Others

DOI: 10.7860/JCDR/2018/32813.11631

Date of Submission: Sep 22, 2017
Date of Peer Review: Nov 02, 2017
Date of Acceptance: Mar 02, 2018
Date of Publishing: Jun 01, 2018

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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