Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2018 | Month : July | Volume : 12 | Issue : 7 | Page : OC09 - OC12

Microbiological Profile of Bronchoalveolar Lavage in Patients with Nosocomial Pneumonia in Intensive Care Unit

Kalyani Sri Koneru, Priya Joy, V Gangadharan, Ashok Kumar, Sathish Kumar

1. Assistant Professor, Department of TB and Chest Medicine, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, India. 2. Postgraduate, Department of TB and Chest Medicine, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, India. 3. Head of the Department, Department of TB and Chest Medicine, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, India. 4. Postgraduate, Department of TB and Chest Medicine, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, India. 5. Assistant Professor, Department of TB and Chest Medicine, Saveetha Medical College and Hospital, Chennai, Tamil Nadu, India.

Correspondence Address :
Dr. Kalyani Sri Koneru,
Ceebros, Shyamala Gardens, 1st Block, Flat No.: 8A Arcot Road, Saligramam, Chennai-600093, Tamil Nadu, India.
E-mail: drkalyanisri@gmail.com

Abstract

Introduction: Intensive Care Units (ICU) are a major threat to nosocomial pneumonias. It is defined as manifestation of infection after 48 hours of hospital admission which can be also attributed to any procedures done to the patient. As resistance to these microorganisms are on the rise in ICU, it is indeed necessary to find out microorganisms and their resistance patterns in ICUs of each institute.

Aim: To find out the most common microorganism with pulmonary involvement in the ICU setup and to determine the sensitivity patterns of microorganisms to the antibiotics by doing Bronchoalveolar Lavage (BAL).

Materials and Methods: A retrospective study was done at a tertiary care centre in Chennai, India, over a period of one year (from January 2017 to December 2017). The study included microbiological reports collected from 92 BAL samples with a diagnosis of pneumonia after 48 hours of ICU admission.

Results: The most common organism isolated was Acinetobacter {36/92 (39%)} followed by Klebsiella Pneumonia {28/92 (31%)} and Pseudomonas {12/92 (13%)}. Acinetobacter was mainly isolated from intubated patients with a sensitivity of 28% to the common broad spectrum antibiotics and 100% to Colistin. While 40% Klebsiella pneumoniae was sensitive to only Colistin and Polymixin, all the Pseudomonas isolates were sensitive to the common broad spectrum antibiotics like Piperacillin-Tazobactum, Amikacin, Cefperazone-Sulbactum.

Conclusion: As per the present study Acinetobacter was the most common organism isolated from ventilator associated pneumonia patients with a high percentage of resistant strains followed by Klebsiella and Pseudomonas. Although, all the microorganisms were sensitive to high level antibiotics only a few were sensitive to the common broad spectrum antibiotics.

Keywords

Antibiotic sensitivity, Hospital acquired pneumonia, Ventilator associated pneumonia

How to cite this article :

Kalyani Sri Koneru, Priya Joy, V Gangadharan, Ashok Kumar, Sathish Kumar. MICROBIOLOGICAL PROFILE OF BRONCHOALVEOLAR LAVAGE IN PATIENTS WITH NOSOCOMIAL PNEUMONIA IN INTENSIVE CARE UNIT. Journal of Clinical and Diagnostic Research [serial online] 2018 July [cited: 2018 Jul 16 ]; 12:OC09-OC12. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=July&volume=12&issue=7&page=OC09-OC12&id=11794

DOI and Others

DOI: 10.7860/JCDR/2018/36708.11794

Date of Submission: Apr 09, 2018
Date of Peer Review: Apr 24, 2018
Date of Acceptance: Jun 01, 2018
Date of Publishing: Jul 01, 2018

FINANCIAL OR OTHER COMPETING INTERESTS: None.

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