Journal of Clinical and Diagnostic Research, ISSN - 0973 - 709X

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Original article / research
Year : 2018 | Month : July | Volume : 12 | Issue : 7 | Page : CC04 - CC06

Evaluation of Dyslipidaemia and Echocardiographic Markers of Myocardial Contractility in Smokers with Ischaemic Heart Disease

Sandhya Metta, Nitin Fal Dessai, Satyanarayana Uppala, Shruti Mohanty, Archana Anand Dharwadkar

1. Assistant Professor, Department of Physiology, KIMS, Narketpally, Nalgonda, Telangana, India. 2. Associate Professor, Department of Biochemistry, KIMS, Narketpally, Nalgonda, Telangana, India. 3. Professor, Department of Biochemistry, Dr. Pinnamaneni Sidhartha Institute of Medical Sciences, Gannavaram, Andhra Pradesh, India 4. Professor, Department of Biochemistry, KIMS, Narketpally, Nalgonda, Telangana, India. 5. Professor and HOD, Department of Biochemistry, KIMS, Narketpally, Nalgonda, Telangana, India.

Correspondence Address :
Dr. Nitin Fal Dessai,
Associate Professor, Department of Biochemistry, KIMS, Sreepuram, Narketpally,
Nalgonda-508254, Telangana, India.
E-mail: nimmynitin@gmail.com

Abstract

Introduction: Cigarette smoking is responsible for dyslipidaemia and haemodynamic disturbances.

Aim: The present study was conducted to evaluate the parameters of dyslipidaemia and left ventricular ejection fraction in smokers with Ischemic Heart Disease (IHD).

Materials and Methods: Total number of study subjects included 327 males, which included 127 healthy subjects and 200 subjects admitted as IHD patients under the inclusion criteria meant for categorizing chronic smokers. They were subsequently divided into smoker and non-smoker groups and evaluated for lipid profile and 2D echocardiography.

Results: The parameters of lipid profile revealed significant difference (p<0.001) in all lipid parameters except HDL among non-smokers vs smokers in both patient and control groups. The echocardiography analysis suggested significantly (<0.001) reduced ejection fraction in patients with smoking habit compared to without smoking habit.

Conclusion: Chronic smokers with history of =15 pack years should undergo screening for IHD by timely evaluation of ejection fraction along with estimation of lipid profile.

Keywords

Ejection fraction, Lipid profile, Nicotine

How to cite this article :

Sandhya Metta, Nitin Fal Dessai, Satyanarayana Uppala, Shruti Mohanty, Archana Anand Dharwadkar. EVALUATION OF DYSLIPIDAEMIA AND ECHOCARDIOGRAPHIC MARKERS OF MYOCARDIAL CONTRACTILITY IN SMOKERS WITH ISCHAEMIC HEART DISEASE. Journal of Clinical and Diagnostic Research [serial online] 2018 July [cited: 2018 Jul 17 ]; 12:CC04-CC06. Available from
http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2018&month=July&volume=12&issue=7&page=CC04-CC06&id=11811

DOI and Others

DOI: 10.7860/JCDR/2018/35417.11811

Date of Submission: Jan 06, 2018
Date of Peer Review: Mar 28, 2018
Date of Acceptance: Apr 27, 2018
Date of Publishing: Jul 01, 2018

First author is recipient of a research fellowship from
Dr. Xx university of health sciences

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